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Items: 12

1.

3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway.

Lu Z, Cox-Hipkin MA, Windsor WT, Boyapati A.

Mol Cancer Res. 2010 Mar;8(3):421-32. doi: 10.1158/1541-7786.MCR-09-0179. Epub 2010 Mar 2.

2.

Regulation and importance of the PI3K/Akt/mTOR signaling pathway in hematologic malignancies.

Kawauchi K, Ogasawara T, Yasuyama M, Otsuka K, Yamada O.

Anticancer Agents Med Chem. 2009 Nov;9(9):1024-38. Review.

PMID:
19663778
3.

Targeting PDK1 in cancer.

Raimondi C, Falasca M.

Curr Med Chem. 2011;18(18):2763-9. Review.

PMID:
21568903
4.

Functional and therapeutic significance of Akt deregulation in malignant melanoma.

Robertson GP.

Cancer Metastasis Rev. 2005 Jun;24(2):273-85. Review.

PMID:
15986137
5.

Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination.

Di Blasio L, Gagliardi PA, Puliafito A, Primo L.

Cancers (Basel). 2017 Mar 11;9(3). pii: E25. doi: 10.3390/cancers9030025. Review.

6.

Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways.

Bayascas JR.

Cell Cycle. 2008 Oct;7(19):2978-82. Epub 2008 Oct 18. Review.

PMID:
18802401
7.

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.

Fyffe C, Falasca M.

Cancer Manag Res. 2013 Aug 23;5:271-80. doi: 10.2147/CMAR.S35026. eCollection 2013. Review.

8.

PDK1: A signaling hub for cell migration and tumor invasion.

Gagliardi PA, di Blasio L, Primo L.

Biochim Biophys Acta. 2015 Dec;1856(2):178-88. doi: 10.1016/j.bbcan.2015.07.003. Epub 2015 Aug 1. Review.

PMID:
26238471
9.

The emerging role of Nemo-like kinase (NLK) in the regulation of cancers.

Huang Y, Yang Y, He Y, Li J.

Tumour Biol. 2015 Dec;36(12):9147-52. doi: 10.1007/s13277-015-4159-7. Epub 2015 Oct 1. Review.

PMID:
26427665
10.

PI3K signaling in cancer: beyond AKT.

Lien EC, Dibble CC, Toker A.

Curr Opin Cell Biol. 2017 Mar 23;45:62-71. doi: 10.1016/j.ceb.2017.02.007. [Epub ahead of print] Review.

PMID:
28343126
11.

PDK1: At the crossroad of cancer signaling pathways.

Gagliardi PA, Puliafito A, Primo L.

Semin Cancer Biol. 2017 May 1. pii: S1044-579X(17)30110-4. doi: 10.1016/j.semcancer.2017.04.014. [Epub ahead of print] Review.

PMID:
28473254
12.

Regulation mechanism of PDK1 on macrophage metabolism and function.

Yang Y, Kong W, Xia Z, Xiao L, Wang S.

Cell Biochem Funct. 2016 Dec;34(8):546-553. doi: 10.1002/cbf.3235. Review.

PMID:
27935137

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