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Items: 1 to 20 of 30

1.

Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects.

Boekelheide K, Campion SN.

Toxicol Sci. 2010 Mar;114(1):20-4. doi: 10.1093/toxsci/kfp307. Epub 2009 Dec 21.

3.

Contribution of new technologies to characterization and prediction of adverse effects.

Rouquié D, Heneweer M, Botham J, Ketelslegers H, Markell L, Pfister T, Steiling W, Strauss V, Hennes C.

Crit Rev Toxicol. 2015 Feb;45(2):172-83. doi: 10.3109/10408444.2014.986054. Epub 2015 Jan 23. Review.

PMID:
25615431
4.

New directions in toxicity testing.

Krewski D, Westphal M, Al-Zoughool M, Croteau MC, Andersen ME.

Annu Rev Public Health. 2011;32:161-78. doi: 10.1146/annurev-publhealth-031210-101153. Review.

PMID:
21219154
5.

Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways.

Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME.

PLoS One. 2011;6(6):e20887. doi: 10.1371/journal.pone.0020887. Epub 2011 Jun 20. Review.

6.

The future of toxicity testing.

Andersen ME, Al-Zoughool M, Croteau M, Westphal M, Krewski D.

J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):163-96. doi: 10.1080/10937404.2010.483933. Review.

PMID:
20574896
8.

[Safety of medicinal nanoproducts: new areas of toxicological research].

Grudziński IP.

Rocz Panstw Zakl Hig. 2011;62(3):239-46. Review. Polish.

9.

[A new method for evaluating acute toxicity intragastrically for classification of chemical substances].

Rydzyński K, Krysiak B.

Med Pr. 1995;46(4):369-83. Review. Polish.

PMID:
7476151
10.

Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing.

Kroes R, Galli C, Munro I, Schilter B, Tran L, Walker R, Würtzen G.

Food Chem Toxicol. 2000 Feb-Mar;38(2-3):255-312. Review.

PMID:
10717364
11.

Health effects classification and its role in the derivation of minimal risk levels: hepatic effects.

Pohl HR, Chou CH.

Regul Toxicol Pharmacol. 2005 Jul;42(2):161-71. Review.

PMID:
15869832
12.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
13.

Pathway-based toxicity: history, current approaches and liver fibrosis and steatosis as prototypes.

Willett C, Caverly Rae J, Goyak KO, Landesmann B, Minsavage G, Westmoreland C.

ALTEX. 2014;31(4):407-21. doi: 10.14573/altex.1401283. Epub 2014 Jun 23. Review.

PMID:
24954301
14.

Toxicity testing in the 21st century: bringing the vision to life.

Andersen ME, Krewski D.

Toxicol Sci. 2009 Feb;107(2):324-30. doi: 10.1093/toxsci/kfn255. Epub 2008 Dec 12. Review.

PMID:
19074763
15.

Toxicity assessment strategies, data requirements, and risk assessment approaches to derive health based guidance values for non-relevant metabolites of plant protection products.

Dekant W, Melching-Kollmuss S, Kalberlah F.

Regul Toxicol Pharmacol. 2010 Mar;56(2):135-42. doi: 10.1016/j.yrtph.2009.10.003. Epub 2009 Oct 31. Review.

PMID:
19883711
16.

From alternative methods to a new toxicology.

Hartung T.

Eur J Pharm Biopharm. 2011 Apr;77(3):338-49. doi: 10.1016/j.ejpb.2010.12.027. Epub 2010 Dec 30. Review.

PMID:
21195172
17.

The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform.

Shukla SJ, Huang R, Austin CP, Xia M.

Drug Discov Today. 2010 Dec;15(23-24):997-1007. doi: 10.1016/j.drudis.2010.07.007. Epub 2010 Aug 11. Review.

18.

Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?

Seiler A, Oelgeschläger M, Liebsch M, Pirow R, Riebeling C, Tralau T, Luch A.

Arch Toxicol. 2011 Nov;85(11):1361-72. doi: 10.1007/s00204-011-0767-1. Epub 2011 Oct 19. Review.

PMID:
22008952
19.

Integrated testing strategies for use in the EU REACH system.

Grindon C, Combes R, Cronin MT, Roberts DW, Garrod JF.

Altern Lab Anim. 2006 Aug;34(4):407-27. Review.

PMID:
16945008
20.

Toxicity testing in the 21st century: a vision and a strategy.

Gibb S.

Reprod Toxicol. 2008 Jan;25(1):136-8. Epub 2007 Nov 1. Review.

PMID:
18093799

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