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Items: 10

1.

RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways.

Shu FJ, Ramineni S, Hepler JR.

Cell Signal. 2010 Mar;22(3):366-76. doi: 10.1016/j.cellsig.2009.10.005.

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Interactions between Ras and Raf: key regulatory proteins in cellular transformation.

Marshall M.

Mol Reprod Dev. 1995 Dec;42(4):493-9. Review.

PMID:
8607981
5.

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.

Chappell WH, Steelman LS, Long JM, Kempf RC, Abrams SL, Franklin RA, Bäsecke J, Stivala F, Donia M, Fagone P, Malaponte G, Mazzarino MC, Nicoletti F, Libra M, Maksimovic-Ivanic D, Mijatovic S, Montalto G, Cervello M, Laidler P, Milella M, Tafuri A, Bonati A, Evangelisti C, Cocco L, Martelli AM, McCubrey JA.

Oncotarget. 2011 Mar;2(3):135-64. Review.

6.

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M, Tafuri A, Stivala F, Libra M, Basecke J, Evangelisti C, Martelli AM, Franklin RA.

Biochim Biophys Acta. 2007 Aug;1773(8):1263-84. Epub 2006 Oct 7. Review.

7.

Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade.

Avruch J, Khokhlatchev A, Kyriakis JM, Luo Z, Tzivion G, Vavvas D, Zhang XF.

Recent Prog Horm Res. 2001;56:127-55. Review.

PMID:
11237210
8.

Mechanistic principles of RAF kinase signaling.

Udell CM, Rajakulendran T, Sicheri F, Therrien M.

Cell Mol Life Sci. 2011 Feb;68(4):553-65. doi: 10.1007/s00018-010-0520-6. Epub 2010 Sep 6. Review.

PMID:
20820846
9.

Regulation of RAF protein kinases in ERK signalling.

Lavoie H, Therrien M.

Nat Rev Mol Cell Biol. 2015 May;16(5):281-98. doi: 10.1038/nrm3979. Review.

PMID:
25907612
10.

Key role of ERK1/2 molecular scaffolds in heart pathology.

Tarone G, Sbroggiò M, Brancaccio M.

Cell Mol Life Sci. 2013 Nov;70(21):4047-54. doi: 10.1007/s00018-013-1321-5. Epub 2013 Mar 27. Review.

PMID:
23532408

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