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Items: 1 to 20 of 1242

1.

Novel trends in high-throughput screening.

Mayr LM, Bojanic D.

Curr Opin Pharmacol. 2009 Oct;9(5):580-8. doi: 10.1016/j.coph.2009.08.004. Epub 2009 Sep 21. Review.

PMID:
19775937
2.

Technological advances in high-throughput screening.

Liu B, Li S, Hu J.

Am J Pharmacogenomics. 2004;4(4):263-76. Review.

PMID:
15287820
3.

High impact technologies for natural products screening.

Koehn FE.

Prog Drug Res. 2008;65:175, 177-210. Review.

PMID:
18084916
4.

Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.

Bergsdorf C, Ottl J.

Expert Opin Drug Discov. 2010 Nov;5(11):1095-107. doi: 10.1517/17460441.2010.524641. Epub 2010 Oct 7. Review.

PMID:
22827747
5.

The impact of diversity-based, high-throughput screening on drug discovery: "chance favours the prepared mind".

Snowden M, Green DV.

Curr Opin Drug Discov Devel. 2008 Jul;11(4):553-8. Review.

PMID:
18600571
6.

Which aspects of HTS are empirically correlated with downstream success?

Bender A, Bojanic D, Davies JW, Crisman TJ, Mikhailov D, Scheiber J, Jenkins JL, Deng Z, Hill WA, Popov M, Jacoby E, Glick M.

Curr Opin Drug Discov Devel. 2008 May;11(3):327-37. Review.

PMID:
18428086
7.

Hit finding: towards 'smarter' approaches.

Langer T, Hoffmann R, Bryant S, Lesur B.

Curr Opin Pharmacol. 2009 Oct;9(5):589-93. doi: 10.1016/j.coph.2009.06.001. Epub 2009 Jul 1. Review.

PMID:
19576852
8.

Tackling the chemogenomic space by novel screening technologies.

Mayr LM.

Ernst Schering Res Found Workshop. 2006;(58):111-73. Review.

PMID:
16709002
9.

Recent trends and observations in the design of high-quality screening collections.

Renner S, Popov M, Schuffenhauer A, Roth HJ, Breitenstein W, Marzinzik A, Lewis I, Krastel P, Nigsch F, Jenkins J, Jacoby E.

Future Med Chem. 2011 Apr;3(6):751-66. doi: 10.4155/fmc.11.15. Review.

PMID:
21554080
10.

Virtual screening for the discovery of bioactive natural products.

Rollinger JM, Stuppner H, Langer T.

Prog Drug Res. 2008;65:211, 213-49. Review.

PMID:
18084917
11.

Affinity-based screening techniques for enhancing lead discovery.

Comess KM, Schurdak ME.

Curr Opin Drug Discov Devel. 2004 Jul;7(4):411-6. Review.

PMID:
15338950
12.

Recent progress in fragment-based lead discovery.

Schulz MN, Hubbard RE.

Curr Opin Pharmacol. 2009 Oct;9(5):615-21. doi: 10.1016/j.coph.2009.04.009. Epub 2009 May 27. Review.

PMID:
19477685
13.

From drug target to leads--sketching a physicochemical pathway for lead molecule design in silico.

Shaikh SA, Jain T, Sandhu G, Latha N, Jayaram B.

Curr Pharm Des. 2007;13(34):3454-70. Review.

PMID:
18220783
14.

Biophysical techniques for ligand screening and drug design.

Renaud JP, Delsuc MA.

Curr Opin Pharmacol. 2009 Oct;9(5):622-8. doi: 10.1016/j.coph.2009.06.008. Epub 2009 Jul 4. Review.

PMID:
19581126
15.

High throughput screening methodologies classified for major drug target classes according to target signaling pathways.

Kool J, Lingeman H, Niessen W, Irth H.

Comb Chem High Throughput Screen. 2010 Jul;13(6):548-61. Review.

PMID:
20429869
16.

NMR-based screening methods for lead discovery.

Vogtherr M, Fiebig K.

EXS. 2003;(93):183-202. Review.

PMID:
12613177
17.

Immunoassays: biological tools for high throughput screening and characterisation of combinatorial libraries.

Taipa MA.

Comb Chem High Throughput Screen. 2008 May;11(4):325-35. Review.

PMID:
18473742
18.

Integration of virtual and high throughput screening in lead discovery settings.

Polgár T, Keseru GM.

Comb Chem High Throughput Screen. 2011 Dec;14(10):889-97. Review.

PMID:
21843143
19.

Recent developments in focused library design: targeting gene-families.

Miller JL.

Curr Top Med Chem. 2006;6(1):19-29. Review.

PMID:
16454755
20.

Advances in improving the quality and flexibility of compound management.

Janzen WP, Popa-Burke IG.

J Biomol Screen. 2009 Jun;14(5):444-51. doi: 10.1177/1087057109335262. Epub 2009 May 29. Review.

PMID:
19483148

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