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Items: 4


Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells.

Lee JI, Nian H, Cooper AJ, Sinha R, Dai J, Bisson WH, Dashwood RH, Pinto JT.

Cancer Prev Res (Phila). 2009 Jul;2(7):683-93. doi: 10.1158/1940-6207.CAPR-09-0047.


Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds.

Pinto JT, Lee JI, Sinha R, MacEwan ME, Cooper AJ.

Amino Acids. 2011 Jun;41(1):29-41. doi: 10.1007/s00726-010-0578-3. Epub 2010 Apr 10. Review.


The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants.

Cooper AJ.

Neurochem Int. 2004 Jun;44(8):557-77. Review. Erratum in: Neurochem Int. 2004 Oct;45(5):783.


Metabolism as a key to histone deacetylase inhibition.

Rajendran P, Williams DE, Ho E, Dashwood RH.

Crit Rev Biochem Mol Biol. 2011 Jun;46(3):181-99. doi: 10.3109/10409238.2011.557713. Epub 2011 Apr 5. Review.

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