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Items: 1 to 20 of 29

1.

The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

Hennah W, Porteous D.

PLoS One. 2009;4(3):e4906. doi: 10.1371/journal.pone.0004906. Epub 2009 Mar 20.

2.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.

Millar JK, Mackie S, Clapcote SJ, Murdoch H, Pickard BS, Christie S, Muir WJ, Blackwood DH, Roder JC, Houslay MD, Porteous DJ.

J Physiol. 2007 Oct 15;584(Pt 2):401-5. Epub 2007 Sep 6. Review.

3.

DISC1 at 10: connecting psychiatric genetics and neuroscience.

Porteous DJ, Millar JK, Brandon NJ, Sawa A.

Trends Mol Med. 2011 Dec;17(12):699-706. doi: 10.1016/j.molmed.2011.09.002. Epub 2011 Oct 19. Review.

4.

Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses.

Sawamura N, Sawa A.

Ann N Y Acad Sci. 2006 Nov;1086:126-33. Review.

PMID:
17185511
5.

Role of DISC1 in neural development and schizophrenia.

Mackie S, Millar JK, Porteous DJ.

Curr Opin Neurobiol. 2007 Feb;17(1):95-102. Epub 2007 Jan 26. Review.

PMID:
17258902
6.

Understanding the role of DISC1 in psychiatric disease and during normal development.

Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A.

J Neurosci. 2009 Oct 14;29(41):12768-75. doi: 10.1523/JNEUROSCI.3355-09.2009. Review.

7.

Linking neurodevelopmental and synaptic theories of mental illness through DISC1.

Brandon NJ, Sawa A.

Nat Rev Neurosci. 2011 Nov 18;12(12):707-22. doi: 10.1038/nrn3120. Review.

8.

How has DISC1 enabled drug discovery?

Wang Q, Jaaro-Peled H, Sawa A, Brandon NJ.

Mol Cell Neurosci. 2008 Feb;37(2):187-95. Epub 2007 Oct 23. Review.

PMID:
18055216
9.

The DISC locus in psychiatric illness.

Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK.

Mol Psychiatry. 2008 Jan;13(1):36-64. Epub 2007 Oct 2. Review.

PMID:
17912248
10.

Regulation of the cytoskeleton by Disrupted-in-schizophrenia 1 (DISC1).

Wang Q, Brandon NJ.

Mol Cell Neurosci. 2011 Dec;48(4):359-64. doi: 10.1016/j.mcn.2011.06.004. Epub 2011 Jun 12. Review.

PMID:
21757008
11.

Disrupted-In-Schizophrenia-1 (DISC1) interactome and mental disorders: impact of mouse models.

Lipina TV, Roder JC.

Neurosci Biobehav Rev. 2014 Sep;45:271-94. doi: 10.1016/j.neubiorev.2014.07.001. Epub 2014 Jul 9. Review.

PMID:
25016072
12.

DISC1 as a therapeutic target for mental illnesses.

Hikida T, Gamo NJ, Sawa A.

Expert Opin Ther Targets. 2012 Dec;16(12):1151-60. doi: 10.1517/14728222.2012.719879. Epub 2012 Nov 6. Review.

13.

The genetics and biology of DISC1--an emerging role in psychosis and cognition.

Porteous DJ, Thomson P, Brandon NJ, Millar JK.

Biol Psychiatry. 2006 Jul 15;60(2):123-31. Review.

PMID:
16843095
14.

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Matsuzaki S, Tohyama M.

Neurochem Int. 2007 Jul-Sep;51(2-4):165-72. Epub 2007 Jun 27. Review.

PMID:
17664024
15.

What can we learn from the disrupted in schizophrenia 1 interactome: lessons for target identification and disease biology?

Camargo LM, Wang Q, Brandon NJ.

Novartis Found Symp. 2008;289:208-16; discussion 216-21, 238-40. Review.

PMID:
18497105
16.

DISC1-binding proteins in neural development, signalling and schizophrenia.

Bradshaw NJ, Porteous DJ.

Neuropharmacology. 2012 Mar;62(3):1230-41. doi: 10.1016/j.neuropharm.2010.12.027. Epub 2010 Dec 31. Review.

17.

DISC1: a key lead in studying cortical development and associated brain disorders.

Narayan S, Nakajima K, Sawa A.

Neuroscientist. 2013 Oct;19(5):451-64. doi: 10.1177/1073858412470168. Epub 2013 Jan 8. Review.

18.

Identification of high risk DISC1 protein structural variants in patients with bipolar spectrum disorder.

Song W, Li W, Noltner K, Yan J, Green E, Grozeva D, Jones IR, Craddock N, Longmate J, Feng J, Sommer SS.

Neurosci Lett. 2010 Dec 17;486(3):136-40. doi: 10.1016/j.neulet.2010.09.027. Epub 2010 Sep 17. Review.

PMID:
20850505
19.

Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.

Hennah W, Thomson P, Peltonen L, Porteous D.

Schizophr Bull. 2006 Jul;32(3):409-16. Epub 2006 May 12. Review.

20.

Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review.

Duff BJ, Macritchie KAN, Moorhead TWJ, Lawrie SM, Blackwood DHR.

Schizophr Res. 2013 Jun;147(1):1-13. doi: 10.1016/j.schres.2013.03.015. Epub 2013 Apr 16. Review.

PMID:
23602339

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