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Items: 6

1.

Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.

Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E.

J Med Chem. 2009 Feb 26;52(4):976-88. doi: 10.1021/jm801023u.

2.

Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents.

Kourounakis AP, Katselou MG, Matralis AN, Ladopoulou EM, Bavavea E.

Curr Med Chem. 2011;18(29):4418-39. Review.

PMID:
21864285
3.

Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase.

Bergstrom JD, Dufresne C, Bills GF, Nallin-Omstead M, Byrne K.

Annu Rev Microbiol. 1995;49:607-39. Review.

PMID:
8561474
4.

Squalene synthase inhibitors : clinical pharmacology and cholesterol-lowering potential.

Charlton-Menys V, Durrington PN.

Drugs. 2007;67(1):11-6. Review.

PMID:
17209661
5.

Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway.

Do R, Kiss RS, Gaudet D, Engert JC.

Clin Genet. 2009 Jan;75(1):19-29. doi: 10.1111/j.1399-0004.2008.01099.x. Epub 2008 Nov 27. Review.

PMID:
19054015
6.

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