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Items: 20

1.

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification.

Buehler PW, Abraham B, Vallelian F, Linnemayr C, Pereira CP, Cipollo JF, Jia Y, Mikolajczyk M, Boretti FS, Schoedon G, Alayash AI, Schaer DJ.

Blood. 2009 Mar 12;113(11):2578-86. doi: 10.1182/blood-2008-08-174466. Epub 2009 Jan 8.

2.

Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a scavenger receptor.

Schaer DJ, Alayash AI, Buehler PW.

Antioxid Redox Signal. 2007 Jul;9(7):991-9. Review.

PMID:
17508920
3.

The haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavenging.

Thomsen JH, Etzerodt A, Svendsen P, Moestrup SK.

Oxid Med Cell Longev. 2013;2013:523652. doi: 10.1155/2013/523652. Epub 2013 May 27. Review.

4.

CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma.

Graversen JH, Madsen M, Moestrup SK.

Int J Biochem Cell Biol. 2002 Apr;34(4):309-14. Review.

PMID:
11854028
5.

Trapping of human hemoglobin by haptoglobin: molecular mechanisms and clinical applications.

Ratanasopa K, Chakane S, Ilyas M, Nantasenamat C, Bulow L.

Antioxid Redox Signal. 2013 Jun 10;18(17):2364-74. doi: 10.1089/ars.2012.4878. Epub 2012 Oct 18. Review.

PMID:
22900934
6.
7.

CD163 and inflammation: biological, diagnostic, and therapeutic aspects.

Etzerodt A, Moestrup SK.

Antioxid Redox Signal. 2013 Jun 10;18(17):2352-63. doi: 10.1089/ars.2012.4834. Epub 2012 Oct 19. Review.

8.

Hemoglobin and heme scavenger receptors.

Nielsen MJ, Møller HJ, Moestrup SK.

Antioxid Redox Signal. 2010 Feb;12(2):261-73. doi: 10.1089/ars.2009.2792. Review.

PMID:
19659436
9.

Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging.

Nielsen MJ, Moestrup SK.

Blood. 2009 Jul 23;114(4):764-71. doi: 10.1182/blood-2009-01-198309. Epub 2009 Apr 20. Review.

10.

Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy.

Van Gorp H, Delputte PL, Nauwynck HJ.

Mol Immunol. 2010 Apr;47(7-8):1650-60. doi: 10.1016/j.molimm.2010.02.008. Epub 2010 Mar 17. Review.

PMID:
20299103
11.

Haptoglobin polymorphism and body iron stores.

Delanghe JR, Langlois MR.

Clin Chem Lab Med. 2002 Mar;40(3):212-6. Review.

PMID:
12005209
12.

Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies.

Schaer DJ, Buehler PW.

Cold Spring Harb Perspect Med. 2013 Jun 1;3(6). pii: a013433. doi: 10.1101/cshperspect.a013433. Review.

13.

Natural history of the bruise: formation, elimination, and biological effects of oxidized hemoglobin.

Jeney V, Eaton JW, Balla G, Balla J.

Oxid Med Cell Longev. 2013;2013:703571. doi: 10.1155/2013/703571. Epub 2013 May 16. Review.

14.

CD163: a regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response.

Moestrup SK, Møller HJ.

Ann Med. 2004;36(5):347-54. Review.

PMID:
15478309
15.

Haptoglobin and CD163: captor and receptor gating hemoglobin to macrophage lysosomes.

Madsen M, Graversen JH, Moestrup SK.

Redox Rep. 2001;6(6):386-8. Review.

PMID:
11865982
16.

Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development.

Schaer DJ, Vinchi F, Ingoglia G, Tolosano E, Buehler PW.

Front Physiol. 2014 Oct 28;5:415. doi: 10.3389/fphys.2014.00415. eCollection 2014 Oct 28. Review.

17.

Haptoglobin: old protein with new functions.

Alayash AI.

Clin Chim Acta. 2011 Mar 18;412(7-8):493-8. doi: 10.1016/j.cca.2010.12.011. Epub 2010 Dec 13. Review.

PMID:
21159311
18.

Evolutionary aspects of hemoglobin scavengers.

Wicher KB, Fries E.

Antioxid Redox Signal. 2010 Feb;12(2):249-59. doi: 10.1089/ars.2009.2760. Review.

PMID:
19650711
19.

Erythrocytes, leukocytes and platelets as a source of oxidative stress in chronic vascular diseases: detoxifying mechanisms and potential therapeutic options.

Martin-Ventura JL, Madrigal-Matute J, Martinez-Pinna R, Ramos-Mozo P, Blanco-Colio LM, Moreno JA, Tarin C, Burillo E, Fernandez-Garcia CE, Egido J, Meilhac O, Michel JB.

Thromb Haemost. 2012 Sep;108(3):435-42. doi: 10.1160/TH12-04-0248. Epub 2012 Jul 26. Review.

PMID:
22836558
20.

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins.

Schaer DJ, Buehler PW, Alayash AI, Belcher JD, Vercellotti GM.

Blood. 2013 Feb 21;121(8):1276-84. doi: 10.1182/blood-2012-11-451229. Epub 2012 Dec 20. Review.

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