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Items: 1 to 20 of 33

1.

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.

Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA.

Cell. 2008 Nov 28;135(5):907-18. doi: 10.1016/j.cell.2008.10.025.

2.

Linking sirtuins, IGF-I signaling, and starvation.

Longo VD.

Exp Gerontol. 2009 Jan-Feb;44(1-2):70-4. doi: 10.1016/j.exger.2008.06.005. Epub 2008 Jun 24. Review.

PMID:
18638538
3.

SIRT1: roles in aging and cancer.

Kim EJ, Um SJ.

BMB Rep. 2008 Nov 30;41(11):751-6. Review.

4.

Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha).

Hisahara S, Chiba S, Matsumoto H, Horio Y.

J Pharmacol Sci. 2005 Jul;98(3):200-4. Epub 2005 Jul 9. Review.

5.

Sirtuins (histone deacetylases III) in the cellular response to DNA damage--facts and hypotheses.

Kruszewski M, Szumiel I.

DNA Repair (Amst). 2005 Nov 21;4(11):1306-13. Epub 2005 Aug 3. Review.

PMID:
16084131
6.

Retinal aging and sirtuins.

Ozawa Y, Kubota S, Narimatsu T, Yuki K, Koto T, Sasaki M, Tsubota K.

Ophthalmic Res. 2010;44(3):199-203. doi: 10.1159/000316484. Epub 2010 Sep 9. Review.

7.

Diverse and dynamic functions of the Sir silencing complex.

Guarente L.

Nat Genet. 1999 Nov;23(3):281-5. Review.

PMID:
10545947
8.

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions.

Zhang T, Kraus WL.

Biochim Biophys Acta. 2010 Aug;1804(8):1666-75. doi: 10.1016/j.bbapap.2009.10.022. Epub 2009 Oct 30. Review.

9.

Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging.

Jia G, Su L, Singhal S, Liu X.

Mol Cell Biochem. 2012 May;364(1-2):345-50. doi: 10.1007/s11010-012-1236-8. Review.

PMID:
22286818
10.

Chromatin regulation and genome maintenance by mammalian SIRT6.

Tennen RI, Chua KF.

Trends Biochem Sci. 2011 Jan;36(1):39-46. doi: 10.1016/j.tibs.2010.07.009. Epub 2010 Aug 21. Review.

11.

Sorting out functions of sirtuins in cancer.

Roth M, Chen WY.

Oncogene. 2014 Mar 27;33(13):1609-20. doi: 10.1038/onc.2013.120. Epub 2013 Apr 22. Review.

12.

The Sir2 family of protein deacetylases.

Blander G, Guarente L.

Annu Rev Biochem. 2004;73:417-35. Review.

PMID:
15189148
13.

SIRT1 regulates the ribosomal DNA locus: epigenetic candles twinkle longevity in the Christmas tree.

Salminen A, Kaarniranta K.

Biochem Biophys Res Commun. 2009 Jan 2;378(1):6-9. doi: 10.1016/j.bbrc.2008.11.023. Epub 2008 Nov 21. Review.

PMID:
19010308
14.

Role of Sirtuins in Maintenance of Genomic Stability: Relevance to Cancer and Healthy Aging.

Wu X, Cao N, Fenech M, Wang X.

DNA Cell Biol. 2016 Oct;35(10):542-575. Epub 2016 Jul 5. Review.

PMID:
27380140
15.

DNA repair, genome stability, and aging.

Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW.

Cell. 2005 Feb 25;120(4):497-512. Review.

16.

Sirtuins in stress response: guardians of the genome.

Bosch-Presegué L, Vaquero A.

Oncogene. 2014 Jul 17;33(29):3764-75. doi: 10.1038/onc.2013.344. Epub 2013 Sep 2. Review.

PMID:
23995787
17.

Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics.

Aggarwal M, Brosh RM Jr.

DNA Repair (Amst). 2012 Apr 1;11(4):335-48. doi: 10.1016/j.dnarep.2012.01.013. Epub 2012 Feb 18. Review.

18.

SIRT6, a protein with many faces.

Gertler AA, Cohen HY.

Biogerontology. 2013 Dec;14(6):629-39. doi: 10.1007/s10522-013-9478-8. Epub 2013 Nov 10. Review.

PMID:
24213807
19.

Changes in DNA repair during aging.

Gorbunova V, Seluanov A, Mao Z, Hine C.

Nucleic Acids Res. 2007;35(22):7466-74. Epub 2007 Oct 2. Review.

20.

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