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Links from PubMed

Items: 5

1.

Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization.

Iorns E, Lord CJ, Ashworth A.

Biochem J. 2009 Jan 1;417(1):361-70. doi: 10.1042/BJ20081682.

PMID:
18976239
2.

Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells.

Santen RJ, Fan P, Zhang Z, Bao Y, Song RX, Yue W.

Steroids. 2009 Jul;74(7):586-94. doi: 10.1016/j.steroids.2008.11.020. Epub 2008 Dec 7. Review.

PMID:
19138696
3.

RNAi screening for therapeutic targets in human malignancies.

Micklem DR, Lorens JB.

Curr Pharm Biotechnol. 2007 Dec;8(6):337-43. Review.

PMID:
18289042
4.

Novel chemical genetic approaches to the discovery of signal transduction inhibitors.

Shokat K, Velleca M.

Drug Discov Today. 2002 Aug 15;7(16):872-9. Review.

PMID:
12546954
5.

Challenges and opportunities in defining the essential cancer kinome.

Manning BD.

Sci Signal. 2009 Mar 24;2(63):pe15. doi: 10.1126/scisignal.263pe15. Review.

PMID:
19318621

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