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Items: 14

1.

Genetic dissection of gamma-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death.

Kallhoff-Munoz V, Hu L, Chen X, Pautler RG, Zheng H.

J Neurosci. 2008 Oct 29;28(44):11421-31. doi: 10.1523/JNEUROSCI.2873-08.2008.

2.

Presenilin-dependent regulated intramembrane proteolysis and gamma-secretase activity.

McCarthy JV, Twomey C, Wujek P.

Cell Mol Life Sci. 2009 May;66(9):1534-55. doi: 10.1007/s00018-009-8435-9. Review.

PMID:
19189053
3.

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C.

Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. Review.

PMID:
10653281
4.

Processes of beta-amyloid and intracellular cytoplasmic domain generation by presenilin/gamma-secretase.

Tagami S, Okochi M, Fukumori A, Jiang J, Yanagida K, Nakayama T, Morihara T, Tanaka T, Kudo T, Takeda M.

Neurodegener Dis. 2008;5(3-4):160-2. doi: 10.1159/000113690. Review.

PMID:
18322378
5.

The many substrates of presenilin/γ-secretase.

Haapasalo A, Kovacs DM.

J Alzheimers Dis. 2011;25(1):3-28. doi: 10.3233/JAD-2011-101065. Review.

6.

The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.

Shen J, Kelleher RJ 3rd.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):403-9. Review.

7.

Physiological functions of presenilins; beyond γ-secretase.

Stiller I, Lizák B, Bánhegyi G.

Curr Pharm Biotechnol. 2014;15(11):1019-25. Review.

PMID:
25420727
8.

Relationship between presenilinase and gamma-secretase.

Xia W.

Drug News Perspect. 2003 Mar;16(2):69-74. Review.

PMID:
12792666
9.

Function and dysfunction of presenilin.

Shen J.

Neurodegener Dis. 2014;13(2-3):61-3. doi: 10.1159/000354971. Review.

10.

The molecular link between beta- and gamma-secretase activity on the amyloid beta precursor protein.

Tabaton M, Tamagno E.

Cell Mol Life Sci. 2007 Sep;64(17):2211-8. Review.

PMID:
17604999
11.

The gamma/epsilon-secretase-derived APP intracellular domain fragments regulate p53.

Checler F, Sunyach C, Pardossi-Piquard R, Sévalle J, Vincent B, Kawarai T, Girardot N, St George-Hyslop P, da Costa CA.

Curr Alzheimer Res. 2007 Sep;4(4):423-6. Review.

PMID:
17908046
12.

Alzheimer's secretases regulate voltage-gated sodium channels.

Kovacs DM, Gersbacher MT, Kim DY.

Neurosci Lett. 2010 Dec 10;486(2):68-72. doi: 10.1016/j.neulet.2010.08.048. Review.

13.

Presenilin transgenic mice as models of Alzheimer's disease.

Elder GA, Gama Sosa MA, De Gasperi R, Dickstein DL, Hof PR.

Brain Struct Funct. 2010 Mar;214(2-3):127-43. doi: 10.1007/s00429-009-0227-3. Review.

14.

The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease.

Currais A, Hortobágyi T, Soriano S.

Aging (Albany NY). 2009 Apr 28;1(4):363-71. Review.

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