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Items: 1 to 20 of 61

1.

Isolation of hyperactive mutants of mammalian target of rapamycin.

Ohne Y, Takahara T, Hatakeyama R, Matsuzaki T, Noda M, Mizushima N, Maeda T.

J Biol Chem. 2008 Nov 14;283(46):31861-70. doi: 10.1074/jbc.M801546200. Epub 2008 Sep 23.

2.

mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.

Wysocki PJ.

Expert Rev Mol Diagn. 2009 Apr;9(3):231-41. doi: 10.1586/erm.09.8. Review.

PMID:
19379082
3.

Targeting the mTOR pathway in tumor malignancy.

Cheng H, Walls M, Baxi SM, Yin MJ.

Curr Cancer Drug Targets. 2013 Mar;13(3):267-77. Review.

PMID:
23297825
4.

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.

Bracho-Valdés I, Moreno-Alvarez P, Valencia-Martínez I, Robles-Molina E, Chávez-Vargas L, Vázquez-Prado J.

IUBMB Life. 2011 Oct;63(10):896-914. doi: 10.1002/iub.558. Epub 2011 Sep 9. Review.

5.

Mammalian target of rapamycin and the kidney. I. The signaling pathway.

Lieberthal W, Levine JS.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F1-10. doi: 10.1152/ajprenal.00014.2012. Epub 2012 Mar 14. Review.

6.

Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth.

Gibbons JJ, Abraham RT, Yu K.

Semin Oncol. 2009 Dec;36 Suppl 3:S3-S17. doi: 10.1053/j.seminoncol.2009.10.011. Review.

PMID:
19963098
7.

Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.

Babcock JT, Quilliam LA.

Curr Drug Targets. 2011 Jul 1;12(8):1223-31. Review.

PMID:
21561413
8.

Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life.

Weichhart T.

Methods Mol Biol. 2012;821:1-14. doi: 10.1007/978-1-61779-430-8_1. Review.

PMID:
22125056
9.

Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis.

Hoshii T, Matsuda S, Hirao A.

J Biochem. 2014 Aug;156(2):73-83. doi: 10.1093/jb/mvu037. Epub 2014 Jun 23. Review.

PMID:
24962700
10.

Deconstructing mTOR complexes in regulation of Glioblastoma Multiforme and its stem cells.

Jhanwar-Uniyal M, Jeevan D, Neil J, Shannon C, Albert L, Murali R.

Adv Biol Regul. 2013 May;53(2):202-10. doi: 10.1016/j.jbior.2012.10.001. Epub 2012 Oct 26. Review.

PMID:
23231881
11.

AMPK and mTOR in cellular energy homeostasis and drug targets.

Inoki K, Kim J, Guan KL.

Annu Rev Pharmacol Toxicol. 2012;52:381-400. doi: 10.1146/annurev-pharmtox-010611-134537. Epub 2011 Oct 17. Review.

PMID:
22017684
12.

Mammalian target of rapamycin signaling in the podocyte.

Inoki K, Huber TB.

Curr Opin Nephrol Hypertens. 2012 May;21(3):251-7. doi: 10.1097/MNH.0b013e3283520f38. Review.

PMID:
22388550
13.

Mammalian TOR signaling to the AGC kinases.

Su B, Jacinto E.

Crit Rev Biochem Mol Biol. 2011 Dec;46(6):527-47. doi: 10.3109/10409238.2011.618113. Epub 2011 Oct 10. Review.

14.

mTOR Signalling in Health and Disease.

Proud CG.

Biochem Soc Trans. 2011 Apr;39(2):431-6. doi: 10.1042/BST0390431. Review.

PMID:
21428914
15.

mTOR signaling: PLD takes center stage.

Sun Y, Chen J.

Cell Cycle. 2008 Oct;7(20):3118-23. Epub 2008 Oct 27. Review.

PMID:
18927511
16.

mTORC1 signaling: what we still don't know.

Wang X, Proud CG.

J Mol Cell Biol. 2011 Aug;3(4):206-20. doi: 10.1093/jmcb/mjq038. Epub 2010 Dec 7. Review.

PMID:
21138990
17.

Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia.

Hirao A, Hoshii T.

Cancer Sci. 2013 Aug;104(8):977-82. doi: 10.1111/cas.12189. Epub 2013 Jun 9. Review.

18.

mTOR signaling in autophagy regulation in the kidney.

Inoki K.

Semin Nephrol. 2014 Jan;34(1):2-8. doi: 10.1016/j.semnephrol.2013.11.002. Epub 2013 Nov 21. Review.

19.

Mammalian target of rapamycin signaling in cardiac physiology and disease.

Sciarretta S, Volpe M, Sadoshima J.

Circ Res. 2014 Jan 31;114(3):549-64. doi: 10.1161/CIRCRESAHA.114.302022. Review.

20.

mTOR in Brain Physiology and Pathologies.

Bockaert J, Marin P.

Physiol Rev. 2015 Oct;95(4):1157-87. doi: 10.1152/physrev.00038.2014. Review.

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