Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 51

1.

JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.

Vainchenker W, Dusa A, Constantinescu SN.

Semin Cell Dev Biol. 2008 Aug;19(4):385-93. doi: 10.1016/j.semcdb.2008.07.002. Epub 2008 Jul 17. Review.

PMID:
18682296
2.

Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.

Constantinescu SN, Leroy E, Gryshkova V, Pecquet C, Dusa A.

Biochem Soc Trans. 2013 Aug;41(4):1048-54. doi: 10.1042/BST20130084. Review.

PMID:
23863177
3.

Janus kinases in immune cell signaling.

Ghoreschi K, Laurence A, O'Shea JJ.

Immunol Rev. 2009 Mar;228(1):273-87. doi: 10.1111/j.1600-065X.2008.00754.x. Review.

4.

The use of structural biology in Janus kinase targeted drug discovery.

Alicea-Velázquez NL, Boggon TJ.

Curr Drug Targets. 2011 Apr;12(4):546-55. Review.

5.

Lymphoid malignancies: Another face to the Janus kinases.

Scott LM.

Blood Rev. 2013 Mar;27(2):63-70. doi: 10.1016/j.blre.2012.12.004. Epub 2013 Jan 20. Review.

PMID:
23340138
6.

JAK/STAT signaling in hematological malignancies.

Vainchenker W, Constantinescu SN.

Oncogene. 2013 May 23;32(21):2601-13. doi: 10.1038/onc.2012.347. Epub 2012 Aug 6. Review.

PMID:
22869151
7.

The molecular regulation of Janus kinase (JAK) activation.

Babon JJ, Lucet IS, Murphy JM, Nicola NA, Varghese LN.

Biochem J. 2014 Aug 15;462(1):1-13. doi: 10.1042/BJ20140712. Review.

8.

JAK and MPL mutations in myeloid malignancies.

Tefferi A.

Leuk Lymphoma. 2008 Mar;49(3):388-97. doi: 10.1080/10428190801895360. Review.

PMID:
18297515
9.

The Janus kinases (Jaks).

Yamaoka K, Saharinen P, Pesu M, Holt VE 3rd, Silvennoinen O, O'Shea JJ.

Genome Biol. 2004;5(12):253. Epub 2004 Nov 30. Review.

10.

Mining for JAK-STAT mutations in cancer.

Constantinescu SN, Girardot M, Pecquet C.

Trends Biochem Sci. 2008 Mar;33(3):122-31. doi: 10.1016/j.tibs.2007.12.002. Review.

PMID:
18291658
11.

The JAK kinases: not just another kinase drug discovery target.

Wilks AF.

Semin Cell Dev Biol. 2008 Aug;19(4):319-28. doi: 10.1016/j.semcdb.2008.07.020. Epub 2008 Aug 5. Review.

PMID:
18721891
12.

Janus kinases and their role in growth and disease.

Aringer M, Cheng A, Nelson JW, Chen M, Sudarshan C, Zhou YJ, O'Shea JJ.

Life Sci. 1999;64(24):2173-86. Review.

PMID:
10374907
13.

Therapeutic targeting of Janus kinases.

Pesu M, Laurence A, Kishore N, Zwillich SH, Chan G, O'Shea JJ.

Immunol Rev. 2008 Jun;223:132-42. doi: 10.1111/j.1600-065X.2008.00644.x. Review.

14.

The two faces of myeloproliferative neoplasms: Molecular events underlying lymphoid transformation.

Holroyd A, Cross NC, Macdonald DH.

Leuk Res. 2011 Oct;35(10):1279-85. doi: 10.1016/j.leukres.2011.05.037. Epub 2011 Jul 1. Review.

PMID:
21722956
15.

JAK2 the future: therapeutic strategies for JAK-dependent malignancies.

LaFave LM, Levine RL.

Trends Pharmacol Sci. 2012 Nov;33(11):574-82. doi: 10.1016/j.tips.2012.08.005. Epub 2012 Sep 17. Review.

PMID:
22995223
16.

Inhibitors of JAK2 and JAK3: an update on the patent literature 2010 - 2012.

Dymock BW, See CS.

Expert Opin Ther Pat. 2013 Apr;23(4):449-501. doi: 10.1517/13543776.2013.765862. Epub 2013 Feb 1. Review.

PMID:
23367873
17.

Inborn errors of human JAKs and STATs.

Casanova JL, Holland SM, Notarangelo LD.

Immunity. 2012 Apr 20;36(4):515-28. doi: 10.1016/j.immuni.2012.03.016. Review.

18.

Regulation of T cell homeostasis by JAKs and STATs.

Ross JA, Nagy ZS, Cheng H, Stepkowski SM, Kirken RA.

Arch Immunol Ther Exp (Warsz). 2007 Jul-Aug;55(4):231-45. Epub 2007 Jul 23. Review.

PMID:
17659375
19.

JAK/STAT signal transduction: regulators and implication in hematological malignancies.

Valentino L, Pierre J.

Biochem Pharmacol. 2006 Mar 14;71(6):713-21. Epub 2006 Jan 19. Review.

PMID:
16426581
20.

JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications.

Springuel L, Renauld JC, Knoops L.

Haematologica. 2015 Oct;100(10):1240-53. doi: 10.3324/haematol.2015.132142. Review.

Supplemental Content

Support Center