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Items: 1 to 20 of 810

1.

What does systems biology mean for drug development?

Schrattenholz A, Soskić V.

Curr Med Chem. 2008;15(15):1520-8. Review.

PMID:
18537627
2.

Systems biology approaches and tools for analysis of interactomes and multi-target drugs.

Schrattenholz A, Groebe K, Soskic V.

Methods Mol Biol. 2010;662:29-58. doi: 10.1007/978-1-60761-800-3_2. Review.

PMID:
20824465
3.

Recent progress in biomolecular engineering.

Ryu DD, Nam DH.

Biotechnol Prog. 2000 Jan-Feb;16(1):2-16. Review.

PMID:
10662483
5.

Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery.

Berger AB, Vitorino PM, Bogyo M.

Am J Pharmacogenomics. 2004;4(6):371-81. Review.

PMID:
15651898
6.
7.

Systems biology: an evolving approach in drug discovery and development.

Ho RL, Lieu CA.

Drugs R D. 2008;9(4):203-16. Review.

PMID:
18588352
8.

The role of emerging genomics and proteomics technologies in cancer drug target discovery.

Onyango P.

Curr Cancer Drug Targets. 2004 Mar;4(2):111-24. Review.

PMID:
15032664
9.

New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

Hausheer FH, Kochat H, Parker AR, Ding D, Yao S, Hamilton SE, Petluru PN, Leverett BD, Bain SH, Saxe JD.

Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S3-15. Review.

PMID:
12819940
11.

Functional genomics and proteomics--the role of nuclear medicine.

Haberkorn U, Altmann A, Eisenhut M.

Eur J Nucl Med Mol Imaging. 2002 Jan;29(1):115-32. Review.

PMID:
11807614
12.

Emerging therapeutic approaches multi-targeting receptor tyrosine kinases and g protein-coupled receptors in cardiovascular disease.

Flordellis C, Papathanasopoulos P, Lymperopoulos A, Matsoukas J, Paris H.

Cardiovasc Hematol Agents Med Chem. 2007 Apr;5(2):133-45. Review.

PMID:
17430136
13.

Network pharmacology: the next paradigm in drug discovery.

Hopkins AL.

Nat Chem Biol. 2008 Nov;4(11):682-90. doi: 10.1038/nchembio.118. Review.

PMID:
18936753
14.

Druggable targets and targeted drugs: enhancing the development of new therapeutics.

Billingsley ML.

Pharmacology. 2008;82(4):239-44. doi: 10.1159/000157624. Review.

15.

Target profiling of small molecules by chemical proteomics.

Rix U, Superti-Furga G.

Nat Chem Biol. 2009 Sep;5(9):616-24. doi: 10.1038/nchembio.216. Review.

PMID:
19690537
16.
18.

Interaction networks: from protein functions to drug discovery. A review.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Pathol Biol (Paris). 2009 Jun;57(4):324-33. doi: 10.1016/j.patbio.2008.10.004. Review.

PMID:
19070972
19.

Protease proteomics: revealing protease in vivo functions using systems biology approaches.

Doucet A, Overall CM.

Mol Aspects Med. 2008 Oct;29(5):339-58. doi: 10.1016/j.mam.2008.04.003. Review.

PMID:
18571712
20.

Logic models of pathway biology.

Watterson S, Marshall S, Ghazal P.

Drug Discov Today. 2008 May;13(9-10):447-56. doi: 10.1016/j.drudis.2008.03.019. Review.

PMID:
18468563
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