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Items: 1 to 20 of 38

1.

Part-time alpha-secretases: the functional biology of ADAM 9, 10 and 17.

Deuss M, Reiss K, Hartmann D.

Curr Alzheimer Res. 2008 Apr;5(2):187-201. Review.

PMID:
18393804
2.

The "A Disintegrin And Metalloproteases" ADAM10 and ADAM17: novel drug targets with therapeutic potential?

Saftig P, Reiss K.

Eur J Cell Biol. 2011 Jun-Jul;90(6-7):527-35. doi: 10.1016/j.ejcb.2010.11.005. Epub 2010 Dec 30. Review.

PMID:
21194787
3.

A closer look at alpha-secretase.

Postina R.

Curr Alzheimer Res. 2008 Apr;5(2):179-86. Review.

PMID:
18393803
4.

Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and presenilin.

Prox J, Rittger A, Saftig P.

Exp Brain Res. 2012 Apr;217(3-4):331-41. doi: 10.1007/s00221-011-2952-0. Epub 2011 Nov 27. Review.

PMID:
22120156
5.

Alpha-secretase activity of the disintegrin metalloprotease ADAM 10. Influences of domain structure.

Fahrenholz F, Gilbert S, Kojro E, Lammich S, Postina R.

Ann N Y Acad Sci. 2000;920:215-22. Review.

PMID:
11193153
6.

α-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential.

Lichtenthaler SF.

J Neurochem. 2011 Jan;116(1):10-21. doi: 10.1111/j.1471-4159.2010.07081.x. Epub 2010 Dec 2. Review.

7.

(Make) stick and cut loose--disintegrin metalloproteases in development and disease.

Tousseyn T, Jorissen E, Reiss K, Hartmann D.

Birth Defects Res C Embryo Today. 2006 Mar;78(1):24-46. Review.

PMID:
16622847
8.
9.

ADAMs family members as amyloid precursor protein alpha-secretases.

Allinson TM, Parkin ET, Turner AJ, Hooper NM.

J Neurosci Res. 2003 Nov 1;74(3):342-52. Review.

PMID:
14598310
10.

Identification and biology of α-secretase.

Vingtdeux V, Marambaud P.

J Neurochem. 2012 Jan;120 Suppl 1:34-45. doi: 10.1111/j.1471-4159.2011.07477.x. Epub 2011 Nov 28. Review.

11.

Implication of APP secretases in notch signaling.

Hartmann D, Tournoy J, Saftig P, Annaert W, De Strooper B.

J Mol Neurosci. 2001 Oct;17(2):171-81. Review.

PMID:
11816790
12.

Alpha-secretase as a therapeutic target.

Fahrenholz F.

Curr Alzheimer Res. 2007 Sep;4(4):412-7. Review.

PMID:
17908044
13.

The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain.

Saftig P, Lichtenthaler SF.

Prog Neurobiol. 2015 Dec;135:1-20. doi: 10.1016/j.pneurobio.2015.10.003. Epub 2015 Oct 29. Review.

PMID:
26522965
14.

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease.

Hooper NM, Turner AJ.

Curr Med Chem. 2002 Jun;9(11):1107-19. Review.

PMID:
12052175
15.

The ADAM metalloproteinases.

Edwards DR, Handsley MM, Pennington CJ.

Mol Aspects Med. 2008 Oct;29(5):258-89. doi: 10.1016/j.mam.2008.08.001. Epub 2008 Aug 15. Review.

PMID:
18762209
16.

ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk.

Higashiyama S, Nanba D.

Biochim Biophys Acta. 2005 Aug 1;1751(1):110-7. Epub 2004 Dec 8. Review.

PMID:
16054021
17.

Adamalysins. A family of metzincins including TNF-alpha converting enzyme (TACE).

Killar L, White J, Black R, Peschon J.

Ann N Y Acad Sci. 1999 Jun 30;878:442-52. Review.

PMID:
10415747
18.

The Role of the anti-amyloidogenic secretase ADAM10 in shedding the APP-like proteins.

Endres K, Fahrenholz F.

Curr Alzheimer Res. 2012 Feb;9(2):157-64. Review.

PMID:
21605036
19.

Activation of α-secretase cleavage.

Postina R.

J Neurochem. 2012 Jan;120 Suppl 1:46-54. doi: 10.1111/j.1471-4159.2011.07459.x. Epub 2011 Nov 28. Review.

20.

Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration.

Altmeppen HC, Prox J, Puig B, Dohler F, Falker C, Krasemann S, Glatzel M.

FEBS J. 2013 Sep;280(18):4338-47. doi: 10.1111/febs.12196. Epub 2013 Mar 13. Review.

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