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Items: 14

1.

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function.

Serohijos AW, Hegedus T, Aleksandrov AA, He L, Cui L, Dokholyan NV, Riordan JR.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3256-61. doi: 10.1073/pnas.0800254105. Epub 2008 Feb 27.

2.

Decoding F508del misfolding in cystic fibrosis.

Wang XR, Li C.

Biomolecules. 2014 May 6;4(2):498-509. doi: 10.3390/biom4020498. Review.

3.

Assembly of functional CFTR chloride channels.

Riordan JR.

Annu Rev Physiol. 2005;67:701-18. Review.

PMID:
15709975
4.

Revisiting cystic fibrosis transmembrane conductance regulator structure and function.

Hanrahan JW, Wioland MA.

Proc Am Thorac Soc. 2004;1(1):17-21. Review.

PMID:
16113406
5.

Gating of the CFTR Cl- channel by ATP-driven nucleotide-binding domain dimerisation.

Hwang TC, Sheppard DN.

J Physiol. 2009 May 15;587(Pt 10):2151-61. doi: 10.1113/jphysiol.2009.171595. Epub 2009 Mar 30. Review.

6.

Structure and function of the CFTR chloride channel.

Sheppard DN, Welsh MJ.

Physiol Rev. 1999 Jan;79(1 Suppl):S23-45. Review.

7.

Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy.

Kim Chiaw P, Eckford PD, Bear CE.

Essays Biochem. 2011 Sep 7;50(1):233-48. doi: 10.1042/bse0500233. Review.

PMID:
21967060
8.
9.

Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability.

Chong PA, Kota P, Dokholyan NV, Forman-Kay JD.

Cold Spring Harb Perspect Med. 2013 Mar 1;3(3):a009522. doi: 10.1101/cshperspect.a009522. Review.

10.

Functional architecture of the CFTR chloride channel.

Linsdell P.

Mol Membr Biol. 2014 Feb;31(1):1-16. doi: 10.3109/09687688.2013.868055. Epub 2013 Dec 17. Review.

PMID:
24341413
11.

Molecular basis for the ATPase activity of CFTR.

Cheung JC, Kim Chiaw P, Pasyk S, Bear CE.

Arch Biochem Biophys. 2008 Aug 1;476(1):95-100. doi: 10.1016/j.abb.2008.03.033. Epub 2008 Apr 8. Review.

PMID:
18417076
12.

The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability.

Meng X, Clews J, Kargas V, Wang X, Ford RC.

Cell Mol Life Sci. 2017 Jan;74(1):23-38. doi: 10.1007/s00018-016-2386-8. Epub 2016 Oct 12. Review.

13.

Molecular modelling and molecular dynamics of CFTR.

Callebaut I, Hoffmann B, Lehn P, Mornon JP.

Cell Mol Life Sci. 2017 Jan;74(1):3-22. doi: 10.1007/s00018-016-2385-9. Epub 2016 Oct 7. Review.

PMID:
27717958
14.

Polytopic membrane protein folding and assembly in vitro and in vivo.

Booth PJ, High S.

Mol Membr Biol. 2004 May-Jun;21(3):163-70. Review.

PMID:
15204624

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