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Items: 11

1.

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.

Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.

Mol Cell Biol. 2008 Apr;28(8):2825-39. doi: 10.1128/MCB.02076-07. Epub 2008 Feb 19.

2.

The upstreams and downstreams of H3K79 methylation by DOT1L.

Vlaming H, van Leeuwen F.

Chromosoma. 2016 Sep;125(4):593-605. doi: 10.1007/s00412-015-0570-5. Epub 2016 Jan 4. Review.

PMID:
26728620
3.

The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.

Kim W, Choi M, Kim JE.

Cell Cycle. 2014;13(5):726-38. doi: 10.4161/cc.28104. Epub 2014 Feb 6. Review.

4.

The diverse functions of Dot1 and H3K79 methylation.

Nguyen AT, Zhang Y.

Genes Dev. 2011 Jul 1;25(13):1345-58. doi: 10.1101/gad.2057811. Review.

5.

A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.

Anglin JL, Song Y.

J Med Chem. 2013 Nov 27;56(22):8972-83. doi: 10.1021/jm4007752. Epub 2013 Aug 14. Review.

6.

The emerging roles of DOT1L in leukemia and normal development.

McLean CM, Karemaker ID, van Leeuwen F.

Leukemia. 2014 Nov;28(11):2131-8. doi: 10.1038/leu.2014.169. Epub 2014 May 23. Review.

PMID:
24854991
7.

Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond.

Chen CW, Armstrong SA.

Exp Hematol. 2015 Aug;43(8):673-84. doi: 10.1016/j.exphem.2015.05.012. Epub 2015 Jun 25. Review.

8.

Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.

Barry ER, Corry GN, Rasmussen TP.

Expert Opin Ther Targets. 2010 Apr;14(4):405-18. doi: 10.1517/14728221003623241. Review.

PMID:
20230194
9.

The many faces of histone H3K79 methylation.

Farooq Z, Banday S, Pandita TK, Altaf M.

Mutat Res Rev Mutat Res. 2016 Apr-Jun;768:46-52. doi: 10.1016/j.mrrev.2016.03.005. Epub 2016 Mar 31. Review.

10.

The role of DOT1L in the maintenance of leukemia gene expression.

Wang X, Chen CW, Armstrong SA.

Curr Opin Genet Dev. 2016 Feb;36:68-72. doi: 10.1016/j.gde.2016.03.015. Epub 2016 May 3. Review.

PMID:
27151433
11.

Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia.

Krivtsov AV, Hoshii T, Armstrong SA.

Cold Spring Harb Perspect Med. 2017 Nov 1;7(11). pii: a026658. doi: 10.1101/cshperspect.a026658. Review.

PMID:
28242784

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