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Items: 13


SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I.

Am J Respir Crit Care Med. 2008 Apr 15;177(8):861-70. doi: 10.1164/rccm.200708-1269OC.


Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases.

Sundar IK, Yao H, Rahman I.

Antioxid Redox Signal. 2013 May 20;18(15):1956-71. doi: 10.1089/ars.2012.4863. Review.


Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD.

Rajendrasozhan S, Yang SR, Edirisinghe I, Yao H, Adenuga D, Rahman I.

Antioxid Redox Signal. 2008 Apr;10(4):799-811. doi: 10.1089/ars.2007.1938. Review.


SIRT1 as a therapeutic target in inflammaging of the pulmonary disease.

Rahman I, Kinnula VL, Gorbunova V, Yao H.

Prev Med. 2012 May;54 Suppl:S20-8. doi: 10.1016/j.ypmed.2011.11.014. Review.


Redox regulation of SIRT1 in inflammation and cellular senescence.

Hwang JW, Yao H, Caito S, Sundar IK, Rahman I.

Free Radic Biol Med. 2013 Aug;61:95-110. doi: 10.1016/j.freeradbiomed.2013.03.015. Review.


Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders.

Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A.

Cell Signal. 2013 Oct;25(10):1939-48. doi: 10.1016/j.cellsig.2013.06.007. Review.


Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease.

Yao H, Rahman I.

Toxicol Appl Pharmacol. 2011 Jul 15;254(2):72-85. doi: 10.1016/j.taap.2009.10.022. Review.


Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD.

Yao H, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 1;303(7):L557-66. doi: 10.1152/ajplung.00175.2012. Review.


Heterogeneity of lung mononuclear phagocytes in chronic obstructive pulmonary disease.

Lee JS.

J Innate Immun. 2012;4(5-6):489-97. doi: 10.1159/000337434. Review.


Extracellular superoxide dismutase and risk of COPD.

Oberley-Deegan RE, Regan EA, Kinnula VL, Crapo JD.

COPD. 2009 Aug;6(4):307-12. Review.


Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulation.

Yu J, Auwerx J.

Pharmacol Res. 2010 Jul;62(1):35-41. doi: 10.1016/j.phrs.2009.12.006. Review.


Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.

Yao H, Rahman I.

Biochem Pharmacol. 2012 Nov 15;84(10):1332-9. doi: 10.1016/j.bcp.2012.06.031. Review.

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