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Items: 1 to 20 of 31

1.

Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes.

Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J.

Biochem Pharmacol. 2007 Oct 15;74(8):1164-71. Epub 2007 Aug 3. Review.

2.

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.

Tsetlin V, Utkin Y, Kasheverov I.

Biochem Pharmacol. 2009 Oct 1;78(7):720-31. doi: 10.1016/j.bcp.2009.05.032. Epub 2009 Jun 6. Review.

PMID:
19501053
3.

Topology of ligand binding sites on the nicotinic acetylcholine receptor.

Arias HR.

Brain Res Brain Res Rev. 1997 Oct;25(2):133-91. Review.

PMID:
9403137
4.
5.

Physical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors.

Molgó J, Aráoz R, Benoit E, Iorga BI.

Expert Opin Drug Discov. 2013 Oct;8(10):1203-23. doi: 10.1517/17460441.2013.822365. Epub 2013 Aug 6. Review.

PMID:
23919818
6.

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.

Holladay MW, Dart MJ, Lynch JK.

J Med Chem. 1997 Dec 19;40(26):4169-94. Review. No abstract available.

PMID:
9435889
7.

Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors.

Arias HR, Bhumireddy P, Bouzat C.

Int J Biochem Cell Biol. 2006;38(8):1254-76. Epub 2006 Feb 20. Review.

PMID:
16520081
8.

The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

Brejc K, van Dijk WJ, Smit AB, Sixma TK.

Novartis Found Symp. 2002;245:22-9; discussion 29-32, 165-8. Review.

PMID:
12027010
9.

Insight in nAChR subtype selectivity from AChBP crystal structures.

Rucktooa P, Smit AB, Sixma TK.

Biochem Pharmacol. 2009 Oct 1;78(7):777-87. doi: 10.1016/j.bcp.2009.06.098. Epub 2009 Jul 1. Review.

PMID:
19576182
10.
11.

Naturally occurring and synthetic peptides acting on nicotinic acetylcholine receptors.

Kasheverov IE, Utkin YN, Tsetlin VI.

Curr Pharm Des. 2009;15(21):2430-52. Review.

PMID:
19601841
12.

Toward atomic-scale understanding of ligand recognition in the muscle nicotinic receptor.

Sine SM, Wang HL, Gao F.

Curr Med Chem. 2004 Mar;11(5):559-67. Review.

PMID:
15032604
13.

Molecular recognition of neonicotinoid insecticides: the determinants of life or death.

Tomizawa M, Casida JE.

Acc Chem Res. 2009 Feb 17;42(2):260-9. doi: 10.1021/ar800131p. Review.

PMID:
19053239
14.

Structure and function of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

Smit AB, Brejc K, Syed N, Sixma TK.

Ann N Y Acad Sci. 2003 Sep;998:81-92. Review.

PMID:
14592865
15.

Ligands of neuronal nicotinic acetylcholine receptor (nAChR): inferences from the Hansch and 3-D quantitative structure-activity relationship (QSAR) Models.

Nicolotti O, Pellegrini-Calace M, Altomar C, Carotti A, Carrieri A, Sanz F.

Curr Med Chem. 2002 Jan;9(1):1-29. Review.

PMID:
11864064
16.

2. Medicinal chemistry of alpha4beta2 nicotinic cholinergic receptor ligands.

Glennon RA.

Prog Med Chem. 2004;42:55-123. Review. No abstract available.

PMID:
15003719
17.

Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy.

Iturriaga-Vásquez P, Alzate-Morales J, Bermudez I, Varas R, Reyes-Parada M.

Pharmacol Res. 2015 Nov;101:9-17. doi: 10.1016/j.phrs.2015.08.018. Epub 2015 Aug 28. Review.

PMID:
26318763
18.

Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure.

Taylor P, Osaka H, Molles BE, Sugiyama N, Marchot P, Ackermann EJ, Malany S, McArdle JJ, Sine SM, Tsigelny I.

J Physiol Paris. 1998 Apr;92(2):79-83. Review.

PMID:
9782448
19.

Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies.

Pandya AA, Yakel JL.

Biochem Pharmacol. 2013 Oct 15;86(8):1054-62. doi: 10.1016/j.bcp.2013.05.018. Epub 2013 May 31. Review.

20.

Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.

Shahsavar A, Gajhede M, Kastrup JS, Balle T.

Basic Clin Pharmacol Toxicol. 2016 Jun;118(6):399-407. doi: 10.1111/bcpt.12528. Epub 2016 Jan 14. Review.

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