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Items: 1 to 20 of 89

1.

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

Williams RS, Williams JS, Tainer JA.

Biochem Cell Biol. 2007 Aug;85(4):509-20. Review.

PMID:
17713585
2.
3.

Dancing on damaged chromatin: functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage.

Iijima K, Ohara M, Seki R, Tauchi H.

J Radiat Res. 2008 Sep;49(5):451-64. Epub 2008 Sep 4. Review.

4.

Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.

Taylor AM, Groom A, Byrd PJ.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1219-25. Review.

PMID:
15279810
5.

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.

Lee JH, Paull TT.

Oncogene. 2007 Dec 10;26(56):7741-8. Review.

PMID:
18066086
6.

The Mre11 complex and ATM: a two-way functional interaction in recognising and signaling DNA double strand breaks.

Lavin MF.

DNA Repair (Amst). 2004 Nov 2;3(11):1515-20. Review. Erratum in: DNA Repair (Amst). 2005 Apr 4;4(4):519.

PMID:
15380107
7.

ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.

Lavin MF.

Oncogene. 2007 Dec 10;26(56):7749-58. Review.

PMID:
18066087
8.

The MRN complex: coordinating and mediating the response to broken chromosomes.

van den Bosch M, Bree RT, Lowndes NF.

EMBO Rep. 2003 Sep;4(9):844-9. Review.

9.

The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer.

Dzikiewicz-Krawczyk A.

Mutat Res. 2008 Sep-Oct;659(3):262-73. doi: 10.1016/j.mrrev.2008.05.005. Epub 2008 Jun 23. Review.

PMID:
18606567
10.

Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.

Lafrance-Vanasse J, Williams GJ, Tainer JA.

Prog Biophys Mol Biol. 2015 Mar;117(2-3):182-93. doi: 10.1016/j.pbiomolbio.2014.12.004. Epub 2015 Jan 7. Review.

11.

Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex.

Matsuura S, Kobayashi J, Tauchi H, Komatsu K.

Adv Biophys. 2004;38:65-80. Review.

PMID:
15493328
12.

Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.

Williams GJ, Lees-Miller SP, Tainer JA.

DNA Repair (Amst). 2010 Dec 10;9(12):1299-306. doi: 10.1016/j.dnarep.2010.10.001. Epub 2010 Oct 28. Review.

13.

MRE11/RAD50/NBS1: complex activities.

Assenmacher N, Hopfner KP.

Chromosoma. 2004 Oct;113(4):157-66. Epub 2004 Aug 10. Review.

PMID:
15309560
14.

ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.

Lavin MF, Kozlov S, Gatei M, Kijas AW.

Biomolecules. 2015 Oct 23;5(4):2877-902. doi: 10.3390/biom5042877. Review.

15.

DNA damage-induced signalling in ataxia-telangiectasia and related syndromes.

Lavin MF, Kozlov S.

Radiother Oncol. 2007 Jun;83(3):231-7. Epub 2007 May 23. Review.

PMID:
17512070
16.

Early events in the mammalian response to DNA double-strand breaks.

Riches LC, Lynch AM, Gooderham NJ.

Mutagenesis. 2008 Sep;23(5):331-9. doi: 10.1093/mutage/gen039. Epub 2008 Jul 21. Review.

PMID:
18644834
17.

Regulation of DNA double-strand break repair pathway choice.

Shrivastav M, De Haro LP, Nickoloff JA.

Cell Res. 2008 Jan;18(1):134-47. Review.

18.

Tip60: connecting chromatin to DNA damage signaling.

Sun Y, Jiang X, Price BD.

Cell Cycle. 2010 Mar 1;9(5):930-6. Epub 2010 Mar 11. Review.

19.

Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair.

Czornak K, Chughtai S, Chrzanowska KH.

J Appl Genet. 2008;49(4):383-96. doi: 10.1007/BF03195638. Review.

PMID:
19029686
20.

Molecular basis of ataxia telangiectasia and related diseases.

Ball LG, Xiao W.

Acta Pharmacol Sin. 2005 Aug;26(8):897-907. Review.

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