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Items: 1 to 20 of 227

1.

Sirtuins: the 'magnificent seven', function, metabolism and longevity.

Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J.

Ann Med. 2007;39(5):335-45. Review.

PMID:
17701476
2.

Calorie restriction and SIR2 genes--towards a mechanism.

Guarente L.

Mech Ageing Dev. 2005 Sep;126(9):923-8. Review.

PMID:
15941577
3.

The role of NAD+ dependent histone deacetylases (sirtuins) in ageing.

Trapp J, Jung M.

Curr Drug Targets. 2006 Nov;7(11):1553-60. Review.

PMID:
17100594
4.

Sir2 and calorie restriction in yeast: a skeptical perspective.

Kaeberlein M, Powers RW 3rd.

Ageing Res Rev. 2007 Aug;6(2):128-40. Epub 2007 Apr 19. Review.

PMID:
17512264
5.

Sirtuins in aging and disease.

Guarente L.

Cold Spring Harb Symp Quant Biol. 2007;72:483-8. doi: 10.1101/sqb.2007.72.024. Review.

PMID:
18419308
6.

Calorie restriction--the SIR2 connection.

Guarente L, Picard F.

Cell. 2005 Feb 25;120(4):473-82. Review.

7.

Calorie restriction increases life span: a molecular mechanism.

Wolf G.

Nutr Rev. 2006 Feb;64(2 Pt 1):89-92. Review.

PMID:
16536186
8.

The anti-aging, metabolism potential of SIRT1.

Ghosh HS.

Curr Opin Investig Drugs. 2008 Oct;9(10):1095-102. Review.

PMID:
18821472
9.

Diversity in the Sir2 family of protein deacetylases.

Buck SW, Gallo CM, Smith JS.

J Leukoc Biol. 2004 Jun;75(6):939-50. Epub 2004 Jan 23. Review.

PMID:
14742637
10.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Haigis MC, Guarente LP.

Genes Dev. 2006 Nov 1;20(21):2913-21. Review.

11.

Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.

Marmorstein R.

Biochem Soc Trans. 2004 Dec;32(Pt 6):904-9. Review.

PMID:
15506920
12.

Sirtuins (histone deacetylases III) in the cellular response to DNA damage--facts and hypotheses.

Kruszewski M, Szumiel I.

DNA Repair (Amst). 2005 Nov 21;4(11):1306-13. Epub 2005 Aug 3. Review.

PMID:
16084131
13.

Function of SIRT1 in physiology.

Kong XX, Wang R, Liu XJ, Zhu LL, Shao D, Chang YS, Fang FD.

Biochemistry (Mosc). 2009 Jul;74(7):703-8. Review.

PMID:
19747089
14.

Sirtuin-targeting drugs: Mechanisms of action and potential therapeutic applications.

Aljada A, Dong L, Mousa SA.

Curr Opin Investig Drugs. 2010 Oct;11(10):1158-68. Review.

PMID:
20872319
15.

Linking sirtuins, IGF-I signaling, and starvation.

Longo VD.

Exp Gerontol. 2009 Jan-Feb;44(1-2):70-4. doi: 10.1016/j.exger.2008.06.005. Epub 2008 Jun 24. Review.

PMID:
18638538
16.
17.

Sirtuins in aging and age-related disease.

Longo VD, Kennedy BK.

Cell. 2006 Jul 28;126(2):257-68. Review.

18.

Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease.

Gan L.

Drug News Perspect. 2007 May;20(4):233-9. Review.

PMID:
17637936
19.

SIRT1: roles in aging and cancer.

Kim EJ, Um SJ.

BMB Rep. 2008 Nov 30;41(11):751-6. Review.

20.

SIR2: a potential target for calorie restriction mimetics.

Chen D, Guarente L.

Trends Mol Med. 2007 Feb;13(2):64-71. Epub 2007 Jan 4. Review.

PMID:
17207661

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