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Items: 17

1.

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.

Tesco G, Koh YH, Kang EL, Cameron AN, Das S, Sena-Esteves M, Hiltunen M, Yang SH, Zhong Z, Shen Y, Simpkins JW, Tanzi RE.

Neuron. 2007 Jun 7;54(5):721-37.

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3.

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential.

Vassar R, Kovacs DM, Yan R, Wong PC.

J Neurosci. 2009 Oct 14;29(41):12787-94. doi: 10.1523/JNEUROSCI.3657-09.2009. Review.

4.
5.

BACE: Therapeutic target and potential biomarker for Alzheimer's disease.

Evin G, Barakat A, Masters CL.

Int J Biochem Cell Biol. 2010 Dec;42(12):1923-6. doi: 10.1016/j.biocel.2010.08.017. Epub 2010 Sep 15. Review.

PMID:
20817005
6.

Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.

Johnston JA, Liu WW, Todd SA, Coulson DT, Murphy S, Irvine GB, Passmore AP.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1096-100. Review.

PMID:
16246054
7.

Amyloid precursor protein and BACE function as oligomers.

Multhaup G.

Neurodegener Dis. 2006;3(4-5):270-4. Review.

PMID:
17047367
8.

Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Vassar R.

Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602. Review.

PMID:
12453676
9.

Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.

Tan J, Evin G.

J Neurochem. 2012 Mar;120(6):869-80. doi: 10.1111/j.1471-4159.2011.07623.x. Epub 2012 Jan 23. Review.

10.

Beta-secretase: structure, function, and evolution.

Venugopal C, Demos CM, Rao KS, Pappolla MA, Sambamurti K.

CNS Neurol Disord Drug Targets. 2008 Jun;7(3):278-94. Review.

11.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
12.

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

Stockley JH, O'Neill C.

Biochem Soc Trans. 2007 Jun;35(Pt 3):574-6. Review.

PMID:
17511655
14.

Brain ischemia activates β- and γ-secretase cleavage of amyloid precursor protein: significance in sporadic Alzheimer's disease.

Pluta R, Furmaga-Jabłońska W, Maciejewski R, Ułamek-Kozioł M, Jabłoński M.

Mol Neurobiol. 2013 Feb;47(1):425-34. doi: 10.1007/s12035-012-8360-z. Epub 2012 Oct 19. Review.

15.

Spotlight on BACE: the secretases as targets for treatment in Alzheimer disease.

Dingwall C.

J Clin Invest. 2001 Nov;108(9):1243-6. Review. No abstract available.

16.

Cell biology, regulation and inhibition of beta-secretase (BACE-1).

Hunt CE, Turner AJ.

FEBS J. 2009 Apr;276(7):1845-59. doi: 10.1111/j.1742-4658.2009.06929.x. Review.

17.

Multiple Targets for the Management of Alzheimer's Disease.

Ahmad SS, Akhtar S, Jamal QM, Rizvi SM, Kamal MA, Khan MK, Siddiqui MH.

CNS Neurol Disord Drug Targets. 2016;15(10):1279-1289. Review.

PMID:
27712576

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