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Items: 1 to 20 of 100

1.

First-generation blood substitutes: what have we learned? Biochemical and physiological perspectives.

Alayash AI, D'Agnillo F, Buehler PW.

Expert Opin Biol Ther. 2007 May;7(5):665-75. Review.

PMID:
17477804
2.

Oxygen therapeutics: can we tame haemoglobin?

Alayash AI.

Nat Rev Drug Discov. 2004 Feb;3(2):152-9. Review.

PMID:
15043006
3.

Site-specific modifications and toxicity of blood substitutes. The case of diaspirin cross-linked hemoglobin.

D'Agnillo F, Alayash AI.

Adv Drug Deliv Rev. 2000 Feb 28;40(3):199-212. Review.

PMID:
10837790
4.

Hemoglobin-based oxygen carriers: From mechanisms of toxicity and clearance to rational drug design.

Buehler PW, D'Agnillo F, Schaer DJ.

Trends Mol Med. 2010 Oct;16(10):447-57. doi: 10.1016/j.molmed.2010.07.006. Epub 2010 Aug 13. Review.

PMID:
20708968
5.

Hemoglobin-based blood substitutes and the hazards of blood radicals.

Alayash AI.

Free Radic Res. 2000 Oct;33(4):341-8. Review.

PMID:
11022843
6.

Redox side reactions of haemoglobin and cell signalling mechanisms.

Yeh LH, Alayash AI.

J Intern Med. 2003 May;253(5):518-26. Review.

7.

Oxidative mechanisms of hemoglobin-based blood substitutes.

Alayash AI.

Artif Cells Blood Substit Immobil Biotechnol. 2001 Nov;29(6):415-25. Review.

PMID:
11795628
8.

Biochemical aspects of the reaction of hemoglobin and NO: implications for Hb-based blood substitutes.

Patel RP.

Free Radic Biol Med. 2000 May 15;28(10):1518-25. Review.

PMID:
10927176
9.

Toxicities of hemoglobin solutions: in search of in-vitro and in-vivo model systems.

Buehler PW, Alayash AI.

Transfusion. 2004 Oct;44(10):1516-30. Review.

PMID:
15383027
10.

Hemoglobin and free radicals: implications for the development of a safe blood substitute.

Alayash AI, Cashon RE.

Mol Med Today. 1995 Jun;1(3):122-7. Review.

PMID:
9415147
11.

Engineering and design of blood substitutes.

Sanders KE, Ackers G, Sligar S.

Curr Opin Struct Biol. 1996 Aug;6(4):534-40. Review.

PMID:
8794165
12.

All hemoglobin-based oxygen carriers are not created equally.

Buehler PW, Alayash AI.

Biochim Biophys Acta. 2008 Oct;1784(10):1378-81. doi: 10.1016/j.bbapap.2007.12.009. Epub 2008 Jan 3. Review.

PMID:
18206989
13.

Allosteric effects on oxidative and nitrosative reactions of cell-free hemoglobins.

Bonaventura C, Henkens R, Alayash AI, Crumbliss AL.

IUBMB Life. 2007 Aug-Sep;59(8-9):498-505. Review.

14.

Molecular controls of the oxygenation and redox reactions of hemoglobin.

Bonaventura C, Henkens R, Alayash AI, Banerjee S, Crumbliss AL.

Antioxid Redox Signal. 2013 Jun 10;18(17):2298-313. doi: 10.1089/ars.2012.4947. Epub 2013 Jan 21. Review.

15.

Radical producing and consuming reactions of hemoglobin: how can we limit toxicity?

Cooper CE.

Artif Organs. 2009 Feb;33(2):110-4. doi: 10.1111/j.1525-1594.2008.00694.x. Review.

PMID:
19178454
16.

Potential uses of hemoglobin-based oxygen carriers in critical care medicine.

Creteur J, Vincent JL.

Crit Care Clin. 2009 Apr;25(2):311-24, Table of Contents. doi: 10.1016/j.ccc.2008.12.011. Review.

PMID:
19341911
17.

Setbacks in blood substitutes research and development: a biochemical perspective.

Alayash AI.

Clin Lab Med. 2010 Jun;30(2):381-9. doi: 10.1016/j.cll.2010.02.009. Epub 2010 May 6. Review.

PMID:
20513557
18.

HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species.

Cabrales P, Friedman JM.

Antioxid Redox Signal. 2013 Jun 10;18(17):2284-97. doi: 10.1089/ars.2012.5099. Epub 2013 Feb 12. Review.

19.

Development of recombinant hemoglobin-based oxygen carriers.

Varnado CL, Mollan TL, Birukou I, Smith BJ, Henderson DP, Olson JS.

Antioxid Redox Signal. 2013 Jun 10;18(17):2314-28. doi: 10.1089/ars.2012.4917. Epub 2012 Nov 16. Review.

20.

Preclinical biology of recombinant human hemoglobin, rHb1.1.

Zuckerman SH, Doyle MP, Gorczynski R, Rosenthal GJ.

Artif Cells Blood Substit Immobil Biotechnol. 1998 May;26(3):231-57. Review.

PMID:
9635118

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