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Items: 1 to 20 of 24

3.

Processive proteolysis by γ-secretase and the mechanism of Alzheimer's disease.

Wolfe MS.

Biol Chem. 2012 Sep;393(9):899-905. doi: 10.1515/hsz-2012-0140. Review.

PMID:
22944690
4.

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C.

Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. Review.

PMID:
10653281
5.

Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.

Supnet C, Bezprozvanny I.

Sci China Life Sci. 2011 Aug;54(8):744-51. doi: 10.1007/s11427-011-4201-y. Epub 2011 Jul 24. Review.

PMID:
21786197
6.

Current insights into molecular mechanisms of Alzheimer disease and their implications for therapeutic approaches.

Van Broeck B, Van Broeckhoven C, Kumar-Singh S.

Neurodegener Dis. 2007;4(5):349-65. Epub 2007 Jul 6. Review.

PMID:
17622778
7.

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms.

Czech C, Tremp G, Pradier L.

Prog Neurobiol. 2000 Mar;60(4):363-84. Review.

PMID:
10670705
8.

The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.

Shen J, Kelleher RJ 3rd.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):403-9. Epub 2006 Dec 29. Review.

9.

Physiological functions of presenilins; beyond γ-secretase.

Stiller I, Lizák B, Bánhegyi G.

Curr Pharm Biotechnol. 2014;15(11):1019-25. Review.

PMID:
25420727
10.

Mechanisms of cell death in Alzheimer's disease: role of presenilins.

Popescu BO, Ankarcrona M.

J Alzheimers Dis. 2004 Apr;6(2):123-8. Review.

PMID:
15096695
11.

Familial Presenilin Mutations and Sporadic Alzheimer's Disease Pathology: Is the Assumption of Biochemical Equivalence Justified?

Roher AE, Maarouf CL, Kokjohn TA.

J Alzheimers Dis. 2016;50(3):645-58. doi: 10.3233/JAD-150757. Review.

PMID:
26757189
12.

Biology of presenilins as causative molecules for Alzheimer disease.

Nishimura M, Yu G, St George-Hyslop PH.

Clin Genet. 1999 Apr;55(4):219-25. Review.

PMID:
10361981
13.

Secretase as a target for Alzheimer's disease.

Wolfe MS.

Curr Top Med Chem. 2002 Apr;2(4):371-83. Review.

PMID:
11966461
14.

Alzheimer's disease sends the wrong signals--a perspective.

Neve RL.

Amyloid. 2008 Mar;15(1):1-4. doi: 10.1080/13506120701814608. Review.

PMID:
18266116
15.
16.

The presenilins and Alzheimer's disease.

Hutton M, Hardy J.

Hum Mol Genet. 1997;6(10):1639-46. Review.

PMID:
9300655
17.

[Alzheimer's disease due to presenilin mutations].

Tabira T.

Nihon Rinsho. 2004 Jan;62 Suppl:90-4. Review. Japanese. No abstract available.

PMID:
15011327
18.

Presenilins as therapeutic targets for the treatment of Alzheimer's disease.

Golde TE, Younkin SG.

Trends Mol Med. 2001 Jun;7(6):264-9. Review.

PMID:
11378516
19.

[Molecular basics of Alzheimer's disease].

Grigorenko AP, Rogaev EI.

Mol Biol (Mosk). 2007 Mar-Apr;41(2):331-45. Review. Russian.

PMID:
17514900
20.

Presenilin mouse and zebrafish models for dementia: focus on neurogenesis.

van Tijn P, Kamphuis W, Marlatt MW, Hol EM, Lucassen PJ.

Prog Neurobiol. 2011 Feb;93(2):149-64. doi: 10.1016/j.pneurobio.2010.10.008. Epub 2010 Nov 5. Review.

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