Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 61

1.

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity.

West AB, Moore DJ, Choi C, Andrabi SA, Li X, Dikeman D, Biskup S, Zhang Z, Lim KL, Dawson VL, Dawson TM.

Hum Mol Genet. 2007 Jan 15;16(2):223-32. Epub 2007 Jan 2.

PMID:
17200152
2.

Contribution of GTPase activity to LRRK2-associated Parkinson disease.

Tsika E, Moore DJ.

Small GTPases. 2013 Jul-Sep;4(3):164-70. doi: 10.4161/sgtp.25130. Epub 2013 Jun 10. Review.

3.

The biology and pathobiology of LRRK2: implications for Parkinson's disease.

Moore DJ.

Parkinsonism Relat Disord. 2008;14 Suppl 2:S92-8. doi: 10.1016/j.parkreldis.2008.04.010. Epub 2008 Jul 7. Review.

PMID:
18602856
4.

LRRK2 pathobiology in Parkinson's disease.

Martin I, Kim JW, Dawson VL, Dawson TM.

J Neurochem. 2014 Dec;131(5):554-65. doi: 10.1111/jnc.12949. Epub 2014 Oct 10. Review.

5.

LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.

Xiong Y, Dawson VL, Dawson TM.

Biochem Soc Trans. 2012 Oct;40(5):1074-9. Review.

6.

Leucine-rich repeat kinase 2: relevance to Parkinson's disease.

Guo L, Wang W, Chen SG.

Int J Biochem Cell Biol. 2006;38(9):1469-75. Epub 2006 Mar 2. Review.

PMID:
16600664
7.

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions.

Greggio E, Cookson MR.

ASN Neuro. 2009 Apr 14;1(1). pii: e00002. doi: 10.1042/AN20090007. Review.

8.

Novel insights into the neurobiology underlying LRRK2-linked Parkinson's disease.

Gómez-Suaga P, Fdez E, Fernández B, Martínez-Salvador M, Blanca Ramírez M, Madero-Pérez J, Rivero-Ríos P, Fuentes JM, Hilfiker S.

Neuropharmacology. 2014 Oct;85:45-56. doi: 10.1016/j.neuropharm.2014.05.020. Epub 2014 May 24. Review.

PMID:
24863040
9.

The neurobiology of LRRK2 and its role in the pathogenesis of Parkinson's disease.

Rideout HJ, Stefanis L.

Neurochem Res. 2014;39(3):576-92. doi: 10.1007/s11064-013-1073-5. Epub 2013 Jun 1. Review.

PMID:
23729298
10.

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease.

Gandhi PN, Chen SG, Wilson-Delfosse AL.

J Neurosci Res. 2009 May 1;87(6):1283-95. doi: 10.1002/jnr.21949. Review.

11.

Molecular biology changes associated with LRRK2 mutations in Parkinson's disease.

Lu YW, Tan EK.

J Neurosci Res. 2008 Jul;86(9):1895-901. doi: 10.1002/jnr.21656. Review.

PMID:
18338801
12.

A trojan horse for Parkinson's disease.

Hu Y, Tong Y.

Sci Signal. 2010 Apr 6;3(116):pe13. doi: 10.1126/scisignal.3116pe13. Review.

PMID:
20371768
13.

Role of LRRK2 kinase activity in the pathogenesis of Parkinson's disease.

Greggio E.

Biochem Soc Trans. 2012 Oct;40(5):1058-62. Review.

PMID:
22988865
14.

Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease.

Biskup S, West AB.

Biochim Biophys Acta. 2009 Jul;1792(7):625-33. doi: 10.1016/j.bbadis.2008.09.015. Epub 2008 Oct 10. Review.

15.

Role of LRRK2 kinase dysfunction in Parkinson disease.

Kumar A, Cookson MR.

Expert Rev Mol Med. 2011 Jun 13;13:e20. doi: 10.1017/S146239941100192X. Review.

16.

LRRK2 in Parkinson's disease: protein domains and functional insights.

Mata IF, Wedemeyer WJ, Farrer MJ, Taylor JP, Gallo KA.

Trends Neurosci. 2006 May;29(5):286-93. Epub 2006 Apr 17. Review.

PMID:
16616379
17.

LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesis.

Esteves AR, Swerdlow RH, Cardoso SM.

Exp Neurol. 2014 Nov;261:206-16. doi: 10.1016/j.expneurol.2014.05.025. Epub 2014 Jun 4. Review.

18.

The GTPase function of LRRK2.

Taymans JM.

Biochem Soc Trans. 2012 Oct;40(5):1063-9. Review.

PMID:
22988866
19.

Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications.

Rudenko IN, Cookson MR.

Neurotherapeutics. 2014 Oct;11(4):738-50. doi: 10.1007/s13311-014-0284-z. Review.

20.

LRRK2 and neurodegeneration.

Santpere G, Ferrer I.

Acta Neuropathol. 2009 Mar;117(3):227-46. doi: 10.1007/s00401-008-0478-8. Epub 2009 Jan 14. Review.

PMID:
19142648

Supplemental Content

Support Center