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Items: 1 to 20 of 52

1.

Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.

Lindström MS, Jin A, Deisenroth C, White Wolf G, Zhang Y.

Mol Cell Biol. 2007 Feb;27(3):1056-68. Epub 2006 Nov 20.

2.

Putting a finger on growth surveillance: insight into MDM2 zinc finger-ribosomal protein interactions.

Lindström MS, Deisenroth C, Zhang Y.

Cell Cycle. 2007 Feb 15;6(4):434-7. Epub 2007 Feb 18. Review.

PMID:
17329973
3.

The RP-Mdm2-p53 pathway and tumorigenesis.

Miliani de Marval PL, Zhang Y.

Oncotarget. 2011 Mar;2(3):234-8. Review.

4.

Unlocking the Mdm2-p53 loop: ubiquitin is the key.

Clegg HV, Itahana K, Zhang Y.

Cell Cycle. 2008 Feb 1;7(3):287-92. Epub 2007 Nov 25. Review.

PMID:
18235222
5.

Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.

Wei J, Yang Y, Lu M, Xu L, Liu F, Yuan Z, Bao Q, Jiang Z, Xu X, Guo X, Zhang X, You Q, Sun H.

Anticancer Agents Med Chem. 2015;16(2):174-89. Review.

PMID:
26343143
6.

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability.

Kim TH, Leslie P, Zhang Y.

Oncotarget. 2014 Feb 28;5(4):860-71. Review.

7.

Functions of the MDM2 oncoprotein.

Freedman DA, Wu L, Levine AJ.

Cell Mol Life Sci. 1999 Jan;55(1):96-107. Review.

PMID:
10065155
8.

p53 ubiquitination: Mdm2 and beyond.

Brooks CL, Gu W.

Mol Cell. 2006 Feb 3;21(3):307-15. Review.

9.

Mdm2 links genotoxic stress and metabolism to p53.

Wang Z, Li B.

Protein Cell. 2010 Dec;1(12):1063-72. doi: 10.1007/s13238-010-0140-9. Epub 2011 Jan 8. Review.

10.

The MDM2-p53 interaction.

Moll UM, Petrenko O.

Mol Cancer Res. 2003 Dec;1(14):1001-8. Review.

11.

MDM2's social network.

Fåhraeus R, Olivares-Illana V.

Oncogene. 2014 Aug 28;33(35):4365-76. doi: 10.1038/onc.2013.410. Epub 2013 Oct 7. Review.

PMID:
24096477
12.

The regulation of MDM2 oncogene and its impact on human cancers.

Zhao Y, Yu H, Hu W.

Acta Biochim Biophys Sin (Shanghai). 2014 Mar;46(3):180-9. doi: 10.1093/abbs/gmt147. Epub 2014 Jan 3. Review.

13.

Mdm2-mediated ubiquitylation: p53 and beyond.

Marine JC, Lozano G.

Cell Death Differ. 2010 Jan;17(1):93-102. doi: 10.1038/cdd.2009.68. Review.

14.

Reactivation of p53 by inhibiting Mdm2 E3 ligase: a novel antitumor approach.

Di J, Zhang Y, Zheng J.

Curr Cancer Drug Targets. 2011 Oct;11(8):987-94. Review.

PMID:
21762075
15.

Signaling to p53: ribosomal proteins find their way.

Zhang Y, Lu H.

Cancer Cell. 2009 Nov 6;16(5):369-77. doi: 10.1016/j.ccr.2009.09.024. Review.

16.

Regulation of the p53 response and its relationship to cancer.

Meek DW.

Biochem J. 2015 Aug 1;469(3):325-46. doi: 10.1042/BJ20150517. Review.

PMID:
26205489
17.

[Progress in regulation of activity and stability of ubiquitin protein ligase MDM2].

Nie J, Tian CY.

Yi Chuan. 2009 Oct;31(10):993-8. Review. Chinese.

PMID:
19840920
18.

Targeting MDM2-p53 interaction for cancer therapy: are we there yet?

Nag S, Zhang X, Srivenugopal KS, Wang MH, Wang W, Zhang R.

Curr Med Chem. 2014;21(5):553-74. Review.

PMID:
24180275
19.

Drug discovery and mutant p53.

Maslon MM, Hupp TR.

Trends Cell Biol. 2010 Sep;20(9):542-55. doi: 10.1016/j.tcb.2010.06.005. Epub 2010 Jul 24. Review.

PMID:
20656489
20.

Distinct roles of MDMX in the regulation of p53 response to ribosomal stress.

Gilkes DM, Chen J.

Cell Cycle. 2007 Jan 15;6(2):151-5. Epub 2007 Jan 13. Review.

PMID:
17327702

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