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Items: 4

1.

Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.

Gazit A, Osherov N, Posner I, Yaish P, Poradosu E, Gilon C, Levitzki A.

J Med Chem. 1991 Jun;34(6):1896-907.

PMID:
1676428
2.

Design and synthesis of novel tyrosine kinase inhibitors using a pharmacophore model of the ATP-binding site of the EGF-R.

Traxler P, Furet P, Mett H, Buchdunger E, Meyer T, Lydon N.

J Pharm Belg. 1997 Mar-Apr;52(2):88-96. Review.

PMID:
9193132
3.
4.

Design of hypoxia-targeting protein tyrosine kinase inhibitor using an innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione.

Hori H, Nagasawa H, Uto Y, Ohkura K, Kirk KL, Uehara Y, Shimamura M.

Biochim Biophys Acta. 2004 Mar 11;1697(1-2):29-38. Review.

PMID:
15023348

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