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Items: 1 to 20 of 80

1.

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation.

López De Jesús M, Stope MB, Oude Weernink PA, Mahlke Y, Börgermann C, Ananaba VN, Rimmbach C, Rosskopf D, Michel MC, Jakobs KH, Schmidt M.

J Biol Chem. 2006 Aug 4;281(31):21837-47. Epub 2006 Jun 5.

2.

Rap-linked cAMP signaling Epac proteins: compartmentation, functioning and disease implications.

Breckler M, Berthouze M, Laurent AC, Crozatier B, Morel E, Lezoualc'h F.

Cell Signal. 2011 Aug;23(8):1257-66. doi: 10.1016/j.cellsig.2011.03.007. Epub 2011 Mar 22. Review.

PMID:
21402149
3.

Ras and Rap1: two highly related small GTPases with distinct function.

Zwartkruis FJ, Bos JL.

Exp Cell Res. 1999 Nov 25;253(1):157-65. Review.

PMID:
10579920
4.

The role of Rap1 in integrin-mediated cell adhesion.

Bos JL, de Bruyn K, Enserink J, Kuiperij B, Rangarajan S, Rehmann H, Riedl J, de Rooij J, van Mansfeld F, Zwartkruis F.

Biochem Soc Trans. 2003 Feb;31(Pt 1):83-6. Review.

PMID:
12546659
5.

Epac and the cardiovascular system.

Schmidt M, Sand C, Jakobs KH, Michel MC, Weernink PA.

Curr Opin Pharmacol. 2007 Apr;7(2):193-200. Epub 2007 Feb 2. Review.

PMID:
17276729
6.

Heptahelical and other G-protein-coupled receptors (GPCRs) signaling.

Landry Y, Niederhoffer N, Sick E, Gies JP.

Curr Med Chem. 2006;13(1):51-63. Review.

PMID:
16457639
7.

Control of Ras cycling by Ca2+.

Walker SA, Cullen PJ, Taylor JA, Lockyer PJ.

FEBS Lett. 2003 Jul 3;546(1):6-10. Review.

8.

Small GTP-binding protein-coupled receptors.

Bhattacharya M, Babwah AV, Ferguson SS.

Biochem Soc Trans. 2004 Dec;32(Pt 6):1040-4. Review.

PMID:
15506958
9.

Functional characterization of the cAMP-binding proteins Epac in cardiac myocytes.

Métrich M, Morel E, Berthouze M, Pereira L, Charron P, Gomez AM, Lezoualc'h F.

Pharmacol Rep. 2009 Jan-Feb;61(1):146-53. Review.

10.

A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases.

Quilliam LA, Rebhun JF, Castro AF.

Prog Nucleic Acid Res Mol Biol. 2002;71:391-444. Review.

PMID:
12102558
11.

Epac proteins: multi-purpose cAMP targets.

Bos JL.

Trends Biochem Sci. 2006 Dec;31(12):680-6. Epub 2006 Nov 2. Review. Erratum in: Trends Biochem Sci. 2007 Jan;32(1):5.

PMID:
17084085
12.

When a G protein-coupled receptor does not couple to a G protein.

Sun Y, McGarrigle D, Huang XY.

Mol Biosyst. 2007 Dec;3(12):849-54. Epub 2007 Oct 4. Review.

PMID:
18000562
13.

Ras regulation and function in lymphocytes.

Genot E, Cantrell DA.

Curr Opin Immunol. 2000 Jun;12(3):289-94. Review.

PMID:
10781411
14.

Evidence for a Ras/Ral signaling cascade.

Feig LA, Urano T, Cantor S.

Trends Biochem Sci. 1996 Nov;21(11):438-41. Review.

PMID:
8987400
15.

cAMP effector mechanisms. Novel twists for an 'old' signaling system.

Kopperud R, Krakstad C, Selheim F, Døskeland SO.

FEBS Lett. 2003 Jul 3;546(1):121-6. Review.

16.

PLC-epsilon: a shared effector protein in Ras-, Rho-, and G alpha beta gamma-mediated signaling.

Wing MR, Bourdon DM, Harden TK.

Mol Interv. 2003 Aug;3(5):273-80. Review.

PMID:
14993441
17.
18.

Cell physiology of cAMP sensor Epac.

Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG.

J Physiol. 2006 Nov 15;577(Pt 1):5-15. Epub 2006 Sep 14. Review.

19.

The Ras binary switch: an ideal processor for decoding complex Ca2+ signals?

Walker SA, Lockyer PJ, Cullen PJ.

Biochem Soc Trans. 2003 Oct;31(Pt 5):966-9. Review.

PMID:
14505461
20.

Sensitization of adenylate cyclase by Galpha i/o-coupled receptors.

Watts VJ, Neve KA.

Pharmacol Ther. 2005 Jun;106(3):405-21. Epub 2005 Mar 2. Review.

PMID:
15922020

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