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Items: 1 to 20 of 136

1.

MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.

Donson AM, Addo-Yobo SO, Handler MH, Gore L, Foreman NK.

Pediatr Blood Cancer. 2007 Apr;48(4):403-7.

PMID:
16609952
2.

Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.

Fukushima T, Takeshima H, Kataoka H.

Anticancer Res. 2009 Nov;29(11):4845-54. Review.

3.

[Role of MGMT and clinical applications in brain tumours].

Paus C, Murat A, Stupp R, Regli L, Hegi M.

Bull Cancer. 2007 Sep;94(9):769-73. Review. French.

4.

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity.

Hegi ME, Liu L, Herman JG, Stupp R, Wick W, Weller M, Mehta MP, Gilbert MR.

J Clin Oncol. 2008 Sep 1;26(25):4189-99. doi: 10.1200/JCO.2007.11.5964. Review.

PMID:
18757334
5.

Treatment considerations for MGMT-unmethylated glioblastoma.

Taylor JW, Schiff D.

Curr Neurol Neurosci Rep. 2015 Jan;15(1):507. doi: 10.1007/s11910-014-0507-z. Review.

PMID:
25394859
6.

Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial.

Mason WP, Cairncross JG.

Nat Clin Pract Neurol. 2005 Dec;1(2):88-95. Review.

PMID:
16932504
7.

Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?

Weller M, Wick W, Hegi ME, Stupp R, Tabatabai G.

Future Oncol. 2010 Sep;6(9):1407-14. doi: 10.2217/fon.10.113. Review.

PMID:
20919826
8.

Association between response to primary treatments and MGMT status in glioblastoma.

Franceschi E, Tosoni A, Pozzati E, Brandes AA.

Expert Rev Anticancer Ther. 2008 Nov;8(11):1781-6. doi: 10.1586/14737140.8.11.1781. Review.

PMID:
18983238
9.

[Strategy for studying gene methylation: the example of MGMT].

Fina F, Nanni-Metellus I, Courdy C, Figarella-Branger D, Martin PM, Ouafik L.

Ann Pathol. 2009 Nov;29 Spec No 1:S37-9. doi: 10.1016/j.annpat.2009.07.015. Review. French. No abstract available.

PMID:
19887248
10.

Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation.

Schiff D.

Cancer Invest. 2007 Dec;25(8):776-84. Review.

PMID:
17952745
11.

[Standards and new developments in the chemotherapy of glioblastomas].

Weller M.

Dtsch Med Wochenschr. 2005 Oct 7;130(40):2270-4. Review. German.

PMID:
16208603
12.

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

Weller M, Stupp R, Reifenberger G, Brandes AA, van den Bent MJ, Wick W, Hegi ME.

Nat Rev Neurol. 2010 Jan;6(1):39-51. doi: 10.1038/nrneurol.2009.197. Review.

PMID:
19997073
13.

Treatment of elderly patients with glioblastoma: a systematic evidence-based analysis.

Zarnett OJ, Sahgal A, Gosio J, Perry J, Berger MS, Chang S, Das S.

JAMA Neurol. 2015 May;72(5):589-96. doi: 10.1001/jamaneurol.2014.3739. Review.

PMID:
25822375
14.

A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.

Jiang G, Wei ZP, Pei DS, Xin Y, Liu YQ, Zheng JN.

Biochem Biophys Res Commun. 2011 Mar 18;406(3):311-4. doi: 10.1016/j.bbrc.2011.02.042. Review.

PMID:
21329652
15.

[Clinicopathological diagnosis of gliomas by genotype analysis].

Nakamura M, Shimada K, Nakase H, Konishi N.

Brain Nerve. 2009 Jul;61(7):773-80. Review. Japanese.

PMID:
19618854
16.

The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.

Garside R, Pitt M, Anderson R, Rogers G, Dyer M, Mealing S, Somerville M, Price A, Stein K.

Health Technol Assess. 2007 Nov;11(45):iii-iv, ix-221. Review.

17.

Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).

Cabrini G, Fabbri E, Lo Nigro C, Dechecchi MC, Gambari R.

Int J Oncol. 2015 Aug;47(2):417-28. doi: 10.3892/ijo.2015.3026. Review.

18.

Prognostic and predictive value of epigenetic silencing of MGMT in patients with high grade gliomas: a systematic review and meta-analysis.

Olson RA, Brastianos PK, Palma DA.

J Neurooncol. 2011 Nov;105(2):325-35. doi: 10.1007/s11060-011-0594-5. Review.

PMID:
21523485
19.

Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.

Johannessen TC, Bjerkvig R.

Expert Rev Anticancer Ther. 2012 May;12(5):635-42. doi: 10.1586/era.12.37. Review.

PMID:
22594898
20.

Treatment of unresectable glioblastoma multiforme.

Nieder C, Grosu AL, Astner S, Molls M.

Anticancer Res. 2005 Nov-Dec;25(6C):4605-10. Review.

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