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Items: 1 to 20 of 44

1.

Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia.

Dong E, Agis-Balboa RC, Simonini MV, Grayson DR, Costa E, Guidotti A.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12578-83. Epub 2005 Aug 19.

2.

The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.

Grayson DR, Chen Y, Costa E, Dong E, Guidotti A, Kundakovic M, Sharma RP.

Pharmacol Ther. 2006 Jul;111(1):272-86. Epub 2006 Mar 30. Review.

PMID:
16574235
3.

GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability.

Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A.

Crit Rev Neurobiol. 2003;15(2):121-42. Review.

PMID:
14977367
4.

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

Guidotti A, Auta J, Davis JM, Dong E, Grayson DR, Veldic M, Zhang X, Costa E.

Psychopharmacology (Berl). 2005 Jul;180(2):191-205. Epub 2005 Apr 28. Review.

PMID:
15864560
5.

Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability.

Costa E, Davis J, Grayson DR, Guidotti A, Pappas GD, Pesold C.

Neurobiol Dis. 2001 Oct;8(5):723-42. Review.

PMID:
11592844
6.

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability.

Costa E, Chen Y, Dong E, Grayson DR, Kundakovic M, Maloku E, Ruzicka W, Satta R, Veldic M, Zhubi A, Guidotti A.

Expert Rev Neurother. 2009 Jan;9(1):87-98. doi: 10.1586/14737175.9.1.87. Review.

PMID:
19102671
7.

Reelin down-regulation in mice and psychosis endophenotypes.

Tueting P, Doueiri MS, Guidotti A, Davis JM, Costa E.

Neurosci Biobehav Rev. 2006;30(8):1065-77. Review.

PMID:
16769115
8.

Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention?

Costa E, Grayson DR, Guidotti A.

Mol Interv. 2003 Jun;3(4):220-9. Review. No abstract available.

PMID:
14993449
9.

Schizophrenia and reelin: a model based on prenatal stress to study epigenetics, brain development and behavior.

Negrón-Oyarzo I, Lara-Vásquez A, Palacios-García I, Fuentealba P, Aboitiz F.

Biol Res. 2016 Mar 11;49:16. doi: 10.1186/s40659-016-0076-5. Review.

10.

REELIN and schizophrenia: a disease at the interface of the genome and the epigenome.

Costa E, Chen Y, Davis J, Dong E, Noh JS, Tremolizzo L, Veldic M, Grayson DR, Guidotti A.

Mol Interv. 2002 Feb;2(1):47-57. Review.

PMID:
14993361
11.

Epigenetic GABAergic targets in schizophrenia and bipolar disorder.

Guidotti A, Auta J, Chen Y, Davis JM, Dong E, Gavin DP, Grayson DR, Matrisciano F, Pinna G, Satta R, Sharma RP, Tremolizzo L, Tueting P.

Neuropharmacology. 2011 Jun;60(7-8):1007-16. doi: 10.1016/j.neuropharm.2010.10.021. Epub 2010 Nov 11. Review.

12.

The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.

Grayson DR, Guidotti A.

Neuropsychopharmacology. 2013 Jan;38(1):138-66. doi: 10.1038/npp.2012.125. Epub 2012 Sep 5. Review.

13.
14.

The involvement of Reelin in neurodevelopmental disorders.

Folsom TD, Fatemi SH.

Neuropharmacology. 2013 May;68:122-35. doi: 10.1016/j.neuropharm.2012.08.015. Epub 2012 Sep 7. Review.

15.

DNA methylation and demethylation as targets for antipsychotic therapy.

Guidotti A, Grayson DR.

Dialogues Clin Neurosci. 2014 Sep;16(3):419-29. Review.

16.

Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders.

Akbarian S, Huang HS.

Brain Res Rev. 2006 Sep;52(2):293-304. Epub 2006 Jun 8. Review.

PMID:
16759710
17.

New neurochemical markers for psychosis: a working hypothesis of their operation.

Guidotti A, Pesold C, Costa E.

Neurochem Res. 2000 Oct;25(9-10):1207-18. Review.

PMID:
11059795
18.

Reelin mouse mutants as models of cortical development disorders.

D'Arcangelo G.

Epilepsy Behav. 2006 Feb;8(1):81-90. Epub 2005 Nov 2. Review.

PMID:
16266828
19.

Epigenetic mechanisms in schizophrenia.

Roth TL, Lubin FD, Sodhi M, Kleinman JE.

Biochim Biophys Acta. 2009 Sep;1790(9):869-77. doi: 10.1016/j.bbagen.2009.06.009. Epub 2009 Jun 25. Review.

20.

Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability.

Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka W, Veldic M.

Epigenetics. 2007 Jan-Mar;2(1):29-36. Epub 2007 Feb 27. Review.

PMID:
17965595

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