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Items: 1 to 20 of 38

1.

Second nature: biological functions of the Raf-1 "kinase".

Baccarini M.

FEBS Lett. 2005 Jun 13;579(15):3271-7. Epub 2005 Mar 23. Review.

2.
3.

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.

Roberts PJ, Der CJ.

Oncogene. 2007 May 14;26(22):3291-310. Review.

PMID:
17496923
4.

Coordinating ERK/MAPK signalling through scaffolds and inhibitors.

Kolch W.

Nat Rev Mol Cell Biol. 2005 Nov;6(11):827-37. Review.

PMID:
16227978
5.

Raf: a strategic target for therapeutic development against cancer.

Beeram M, Patnaik A, Rowinsky EK.

J Clin Oncol. 2005 Sep 20;23(27):6771-90. Review.

PMID:
16170185
6.

Mechanisms of regulating the Raf kinase family.

Chong H, Vikis HG, Guan KL.

Cell Signal. 2003 May;15(5):463-9. Review.

PMID:
12639709
7.

Hyperactive Ras in developmental disorders and cancer.

Schubbert S, Shannon K, Bollag G.

Nat Rev Cancer. 2007 Apr;7(4):295-308. Review. Erratum in: Nat Rev Cancer. 2007 Jul;7(7):563.

PMID:
17384584
8.

Role of raf proteins in cardiac hypertrophy and cardiomyocyte survival.

Muslin AJ.

Trends Cardiovasc Med. 2005 Aug;15(6):225-9. Review.

PMID:
16182133
9.

Targeting the RAF-MEK-ERK pathway in cancer therapy.

Montagut C, Settleman J.

Cancer Lett. 2009 Oct 8;283(2):125-34. doi: 10.1016/j.canlet.2009.01.022. Epub 2009 Feb 12. Review.

PMID:
19217204
10.

Raf kinase as a target for anticancer therapeutics.

Sridhar SS, Hedley D, Siu LL.

Mol Cancer Ther. 2005 Apr;4(4):677-85. Review.

11.

Regulation of c-Raf-1: therapeutic implications.

Beeram M, Patnaik A, Rowinsky EK.

Clin Adv Hematol Oncol. 2003 Aug;1(8):476-81. Review.

PMID:
16258435
12.

Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery.

Thompson N, Lyons J.

Curr Opin Pharmacol. 2005 Aug;5(4):350-6. Review.

PMID:
15955734
13.

Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.

Gollob JA, Wilhelm S, Carter C, Kelley SL.

Semin Oncol. 2006 Aug;33(4):392-406. Review.

PMID:
16890795
14.

[Roles of targeting Ras/Raf/MEK/ERK signaling pathways in the treatment of esophageal carcinoma].

Chang YS, Liu JC, Fu HQ, Yu BT, Zou SB, Wu QC, Wan L.

Yao Xue Xue Bao. 2013 May;48(5):635-41. Review. Chinese.

PMID:
23888683
15.

Isotype-specific functions of Raf kinases.

Hagemann C, Rapp UR.

Exp Cell Res. 1999 Nov 25;253(1):34-46. Review.

PMID:
10579909
16.

Raf kinases in cancer-roles and therapeutic opportunities.

Maurer G, Tarkowski B, Baccarini M.

Oncogene. 2011 Aug 11;30(32):3477-88. doi: 10.1038/onc.2011.160. Epub 2011 May 16. Review.

PMID:
21577205
17.

The role of Raf kinases in malignant transformation.

Kolch W, Kotwaliwale A, Vass K, Janosch P.

Expert Rev Mol Med. 2002 Apr 25;4(8):1-18. Review.

PMID:
14987392
18.

The RAF proteins take centre stage.

Wellbrock C, Karasarides M, Marais R.

Nat Rev Mol Cell Biol. 2004 Nov;5(11):875-85. Review.

PMID:
15520807
19.

Conferring specificity on the ubiquitous Raf/MEK signalling pathway.

O'Neill E, Kolch W.

Br J Cancer. 2004 Jan 26;90(2):283-8. Review.

20.

Targets of Raf in tumorigenesis.

Niault TS, Baccarini M.

Carcinogenesis. 2010 Jul;31(7):1165-74. doi: 10.1093/carcin/bgp337. Epub 2010 Jan 4. Review.

PMID:
20047953

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