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Items: 1 to 20 of 26

1.

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.

Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA.

Nature. 2005 Mar 31;434(7033):644-8. Erratum in: Nature. 2007 Mar 1;446(7131):102.

2.

ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.

Verma P, Dalal K.

J Cell Biochem. 2011 Dec;112(12):3507-14. doi: 10.1002/jcb.23298. Review.

PMID:
21815191
3.

Anti-ADAMTS5 monoclonal antibodies: implications for aggrecanase inhibition in osteoarthritis.

Apte SS.

Biochem J. 2016 Jan 1;473(1):e1-4. doi: 10.1042/BJ20151072. Review.

PMID:
26657033
4.

Aggrecanases and cartilage matrix degradation.

Nagase H, Kashiwagi M.

Arthritis Res Ther. 2003;5(2):94-103. Review.

5.

Mechanisms involved in cartilage proteoglycan catabolism.

Caterson B, Flannery CR, Hughes CE, Little CB.

Matrix Biol. 2000 Aug;19(4):333-44. Review.

PMID:
10963994
6.

The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review.

Bondeson J, Wainwright S, Hughes C, Caterson B.

Clin Exp Rheumatol. 2008 Jan-Feb;26(1):139-45. Review.

PMID:
18328163
7.

[Destruction of the articular cartilage in osteoarthritis].

Okubo M, Okada Y.

Clin Calcium. 2013 Dec;23(12):1705-13. doi: CliCa131217051713. Review. Japanese.

PMID:
24292524
8.

[Role of aggrecanase and MMP in cartilage degradation].

Ishiguro N, Kojima T.

Clin Calcium. 2004 Jul;14(7):38-44. Review. Japanese.

PMID:
15577074
9.

Suppression of aggrecanase: a novel protective mechanism of dehydroepiandrosterone in osteoarthritis?

Huang K, Wu LD.

Mol Biol Rep. 2010 Mar;37(3):1241-5. doi: 10.1007/s11033-009-9495-5. Review.

PMID:
19277895
10.

Upregulation of enzymatic activity by interleukin-1 in osteoarthritis.

Chevalier X.

Biomed Pharmacother. 1997;51(2):58-62. Review.

PMID:
9161468
11.

Extracellular matrix and pathogenic mechanisms in osteoarthritis.

Hardingham T.

Curr Rheumatol Rep. 2008 Jan;10(1):30-6. Review.

PMID:
18457609
12.

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation--divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation.

Sondergaard BC, Schultz N, Madsen SH, Bay-Jensen AC, Kassem M, Karsdal MA.

Osteoarthritis Cartilage. 2010 Mar;18(3):279-88. doi: 10.1016/j.joca.2009.11.005. Review.

13.

Proteolytic degradation in human articular cartilage: its relationship to stromelysin.

Roughley PJ, Nguyen Q, Mort JS, Hughes CE, Caterson B.

Agents Actions Suppl. 1993;39:149-59. Review.

PMID:
8456625
14.

Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail".

Ameye LG, Young MF.

Curr Opin Rheumatol. 2006 Sep;18(5):537-47. Review.

PMID:
16896297
15.

Etiology and pathophysiology of osteoarthritis.

Mandelbaum B, Waddell D.

Orthopedics. 2005 Feb;28(2 Suppl):s207-14. Review.

PMID:
15747608
16.

[Progress of research in osteoarthritis. Molecular targeting for osteoarthritis treatment].

Kawaguchi H.

Clin Calcium. 2009 Nov;19(11):1608-14. doi: CliCa091116081614. Review. Japanese.

PMID:
19880993
17.

In vivo osteoarthritis target validation utilizing genetically-modified mice.

Glasson SS.

Curr Drug Targets. 2007 Feb;8(2):367-76. Review.

PMID:
17305514
18.

Proteases involved in cartilage matrix degradation in osteoarthritis.

Troeberg L, Nagase H.

Biochim Biophys Acta. 2012 Jan;1824(1):133-45. doi: 10.1016/j.bbapap.2011.06.020. Review.

19.

Mechanotransduction and cartilage integrity.

Leong DJ, Hardin JA, Cobelli NJ, Sun HB.

Ann N Y Acad Sci. 2011 Dec;1240:32-7. doi: 10.1111/j.1749-6632.2011.06301.x. Review.

20.

[Progress of research in osteoarthritis. Gene expression and its regulatory mechanisms in the degenerative cartilage in osteoarthritis].

Okazaki K, Iwamoto Y.

Clin Calcium. 2009 Nov;19(11):1578-85. doi: CliCa091115781585. Review. Japanese.

PMID:
19880989
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