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Items: 1 to 20 of 39

1.

Substrate-specific activation of sirtuins by resveratrol.

Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK.

J Biol Chem. 2005 Apr 29;280(17):17038-45. Epub 2005 Jan 31.

2.

The Sir2 family of protein deacetylases.

Blander G, Guarente L.

Annu Rev Biochem. 2004;73:417-35. Review.

PMID:
15189148
3.

Sound silencing: the Sir2 protein and cellular senescence.

Defossez PA, Lin SJ, McNabb DS.

Bioessays. 2001 Apr;23(4):327-32. Review.

PMID:
11268038
4.

NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets.

Schemies J, Uciechowska U, Sippl W, Jung M.

Med Res Rev. 2010 Nov;30(6):861-89. doi: 10.1002/med.20178. Review.

PMID:
19824050
5.

SIRT1 regulates the ribosomal DNA locus: epigenetic candles twinkle longevity in the Christmas tree.

Salminen A, Kaarniranta K.

Biochem Biophys Res Commun. 2009 Jan 2;378(1):6-9. doi: 10.1016/j.bbrc.2008.11.023. Epub 2008 Nov 21. Review.

PMID:
19010308
6.

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors.

Grozinger CM, Schreiber SL.

Chem Biol. 2002 Jan;9(1):3-16. Review. No abstract available.

7.
8.

Identification and characterization of Sir2 inhibitors through phenotypic assays in yeast.

Posakony J, Hirao M, Bedalov A.

Comb Chem High Throughput Screen. 2004 Nov;7(7):661-8. Review.

PMID:
15578928
9.

Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.

Marmorstein R.

Biochem Soc Trans. 2004 Dec;32(Pt 6):904-9. Review.

PMID:
15506920
10.
11.

Resveratrol--a boon for treating Alzheimer's disease?

Anekonda TS.

Brain Res Rev. 2006 Sep;52(2):316-26. Review.

PMID:
16766037
12.

Common themes in mechanisms of gene silencing.

Moazed D.

Mol Cell. 2001 Sep;8(3):489-98. Review.

13.

Sir2 and calorie restriction in yeast: a skeptical perspective.

Kaeberlein M, Powers RW 3rd.

Ageing Res Rev. 2007 Aug;6(2):128-40. Epub 2007 Apr 19. Review.

PMID:
17512264
14.

Modulation of sirtuins: new targets for antiageing.

Pallàs M, Verdaguer E, Tajes M, Gutierrez-Cuesta J, Camins A.

Recent Pat CNS Drug Discov. 2008 Jan;3(1):61-9. Review.

PMID:
18221243
15.

The controversial links among calorie restriction, SIRT1, and resveratrol.

Hu Y, Liu J, Wang J, Liu Q.

Free Radic Biol Med. 2011 Jul 15;51(2):250-6. doi: 10.1016/j.freeradbiomed.2011.04.034. Epub 2011 Apr 22. Review.

PMID:
21569839
16.

AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.

Verdin E.

Mol Cell. 2007 Nov 9;28(3):354-6. Review.

17.

Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation.

Baxter RA.

J Cosmet Dermatol. 2008 Mar;7(1):2-7. doi: 10.1111/j.1473-2165.2008.00354.x. Review.

PMID:
18254804
18.

After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders.

Huber K, Superti-Furga G.

Bioorg Med Chem. 2011 Jun 15;19(12):3616-24. doi: 10.1016/j.bmc.2011.01.018. Epub 2011 Jan 15. Review.

PMID:
21306906
19.

Resveratrol vs. calorie restriction: data from rodents to humans.

Lam YY, Peterson CM, Ravussin E.

Exp Gerontol. 2013 Oct;48(10):1018-24. doi: 10.1016/j.exger.2013.04.005. Epub 2013 Apr 25. Review.

PMID:
23624181
20.

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases.

Ramis MR, Esteban S, Miralles A, Tan DX, Reiter RJ.

Mech Ageing Dev. 2015 Mar;146-148:28-41. doi: 10.1016/j.mad.2015.03.008. Epub 2015 Mar 27. Review.

PMID:
25824609

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