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Items: 19

1.

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.

Lancaster DE, McNeill LA, McDonough MA, Aplin RT, Hewitson KS, Pugh CW, Ratcliffe PJ, Schofield CJ.

Biochem J. 2004 Nov 1;383(Pt. 3):429-37.

2.

Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer.

Hewitson KS, McNeill LA, Schofield CJ.

Curr Pharm Des. 2004;10(8):821-33. Review.

PMID:
15032687
3.

Regulation of HIF: asparaginyl hydroxylation.

Peet D, Linke S.

Novartis Found Symp. 2006;272:37-49; discussion 49-53, 131-40. Review.

PMID:
16686428
4.

The role of iron and 2-oxoglutarate oxygenases in signalling.

Hewitson KS, McNeill LA, Elkins JM, Schofield CJ.

Biochem Soc Trans. 2003 Jun;31(Pt 3):510-5. Review.

PMID:
12773146
5.

FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

Cockman ME, Webb JD, Ratcliffe PJ.

Ann N Y Acad Sci. 2009 Oct;1177:9-18. doi: 10.1111/j.1749-6632.2009.05042.x. Review.

PMID:
19845602
6.

HIF hydroxylation and cellular oxygen sensing.

Metzen E, Ratcliffe PJ.

Biol Chem. 2004 Mar-Apr;385(3-4):223-30. Review.

PMID:
15134335
7.

Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases.

Bruegge K, Jelkmann W, Metzen E.

Curr Med Chem. 2007;14(17):1853-62. Review.

PMID:
17627521
8.

Signalling cross talk of the HIF system: involvement of the FIH protein.

Coleman ML, Ratcliffe PJ.

Curr Pharm Des. 2009;15(33):3904-7. Review.

PMID:
19671041
9.

Hypoxia-inducible factor 1 (HIF-1) pathway.

Semenza GL.

Sci STKE. 2007 Oct 9;2007(407):cm8. Review.

10.

Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression.

Stockmann C, Fandrey J.

Clin Exp Pharmacol Physiol. 2006 Oct;33(10):968-79. Review.

PMID:
17002676
11.

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

Lancaster DE, McDonough MA, Schofield CJ.

Biochem Soc Trans. 2004 Dec;32(Pt 6):943-5. Review.

PMID:
15506931
12.

HIF-1: the knowns and unknowns of hypoxia sensing.

Zagórska A, Dulak J.

Acta Biochim Pol. 2004;51(3):563-85. Review.

13.

Oxygen-sensing under the influence of nitric oxide.

Berchner-Pfannschmidt U, Tug S, Kirsch M, Fandrey J.

Cell Signal. 2010 Mar;22(3):349-56. doi: 10.1016/j.cellsig.2009.10.004. Review.

PMID:
19861159
14.

Proline hydroxylation and gene expression.

Kaelin WG.

Annu Rev Biochem. 2005;74:115-28. Review.

PMID:
15952883
15.

Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential.

Nagarajan Y, Rychkov GY, Peet DJ.

Pharmaceuticals (Basel). 2017 Mar 27;10(2). pii: E35. doi: 10.3390/ph10020035. Review.

16.

New horizons in hypoxia signaling pathways.

Pugh CW, Ratcliffe PJ.

Exp Cell Res. 2017 Jul 15;356(2):116-121. doi: 10.1016/j.yexcr.2017.03.008. Epub 2017 Mar 15. Review.

17.

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives.

Bishop T, Ratcliffe PJ.

Hypoxia (Auckl). 2014 Dec 5;2:197-213. eCollection 2014. Review.

18.

Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression.

Kuiper C, Vissers MC.

Front Oncol. 2014 Dec 10;4:359. doi: 10.3389/fonc.2014.00359. eCollection 2014. Review.

19.

Post-translational hydroxylation by 2OG/Fe(II)-dependent oxygenases as a novel regulatory mechanism in bacteria.

van Staalduinen LM, Jia Z.

Front Microbiol. 2015 Jan 15;5:798. doi: 10.3389/fmicb.2014.00798. eCollection 2014. Review.

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