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Items: 1 to 20 of 35

1.

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease.

Klein WL, Stine WB Jr, Teplow DB.

Neurobiol Aging. 2004 May-Jun;25(5):569-80. Review.

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Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses.

Cerpa W, Dinamarca MC, Inestrosa NC.

Curr Alzheimer Res. 2008 Jun;5(3):233-43. Review.

PMID:
18537540
6.

Role of the region 23-28 in Abeta fibril formation: insights from simulations of the monomers and dimers of Alzheimer's peptides Abeta40 and Abeta42.

Melquiond A, Dong X, Mousseau N, Derreumaux P.

Curr Alzheimer Res. 2008 Jun;5(3):244-50. Review.

PMID:
18537541
7.

The toxic conformation of the 42-residue amyloid beta peptide and its relevance to oxidative stress in Alzheimer's disease.

Irie K, Murakami K, Masuda Y, Morimoto A, Ohigashi H, Hara H, Ohashi R, Takegoshi K, Fukuda H, Nagao M, Shimizu T, Shirasawa T.

Mini Rev Med Chem. 2007 Oct;7(10):1001-8. Review.

PMID:
17979802
8.

The turn formation at positions 22 and 23 in the 42-mer amyloid beta peptide: the emerging role in the pathogenesis of Alzheimer's disease.

Murakami K, Masuda Y, Shirasawa T, Shimizu T, Irie K.

Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S169-79. doi: 10.1111/j.1447-0594.2010.00598.x. Review.

PMID:
20590832
9.

Lethal weapon: amyloid beta-peptide, role in the oxidative stress and neurodegeneration of Alzheimer's disease.

Lahiri DK, Greig NH.

Neurobiol Aging. 2004 May-Jun;25(5):581-7. Review. No abstract available.

PMID:
15172733
10.

Controlling amyloid growth in multiple dimensions.

Dong J, Lu K, Lakdawala A, Mehta AK, Lynn DG.

Amyloid. 2006 Dec;13(4):206-15. Review.

PMID:
17107881
11.

Structure of beta-amyloid fibrils and its relevance to their neurotoxicity: implications for the pathogenesis of Alzheimer's disease.

Irie K, Murakami K, Masuda Y, Morimoto A, Ohigashi H, Ohashi R, Takegoshi K, Nagao M, Shimizu T, Shirasawa T.

J Biosci Bioeng. 2005 May;99(5):437-47. Review.

PMID:
16233815
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Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition.

Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ.

Biochem Soc Trans. 2002 Aug;30(4):552-7. Review.

PMID:
12196135
14.

Always around, never the same: pathways of amyloid beta induced neurodegeneration throughout the pathogenic cascade of Alzheimer's disease.

Hoozemans JJ, Chafekar SM, Baas F, Eikelenboom P, Scheper W.

Curr Med Chem. 2006;13(22):2599-605. Review.

PMID:
17017913
15.

Intracellular amyloid beta-protein and its associated molecules in the pathogenesis of Alzheimer's disease.

Ohyagi Y, Tabira T.

Mini Rev Med Chem. 2006 Oct;6(10):1075-80. Review.

PMID:
17073707
16.

Computer simulations of Alzheimer's amyloid beta-protein folding and assembly.

Urbanc B, Cruz L, Teplow DB, Stanley HE.

Curr Alzheimer Res. 2006 Dec;3(5):493-504. Review.

PMID:
17168648
17.

The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology.

Giuffrida ML, Caraci F, De Bona P, Pappalardo G, Nicoletti F, Rizzarelli E, Copani A.

Rev Neurosci. 2010;21(2):83-93. Review.

PMID:
20614800
18.

Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Abeta(1-42).

Sultana R, Perluigi M, Butterfield DA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Mar 20;833(1):3-11. Epub 2005 Oct 17. Review.

PMID:
16236561
19.

Is covalently crosslinked Abeta responsible for synaptotoxicity in Alzheimer's disease?

Naylor R, Hill AF, Barnham KJ.

Curr Alzheimer Res. 2008 Dec;5(6):533-9. Review.

PMID:
19075579
20.

Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease.

Kirkitadze MD, Kowalska A.

Acta Biochim Pol. 2005;52(2):417-23. Epub 2005 May 31. Review.

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