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Items: 1 to 20 of 31

1.

Mechanistic diversity and regulation of Type II fatty acid synthesis.

Marrakchi H, Zhang YM, Rock CO.

Biochem Soc Trans. 2002 Nov;30(Pt 6):1050-5. Review.

PMID:
12440970
2.

The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.

Zhang YM, Marrakchi H, White SW, Rock CO.

J Lipid Res. 2003 Jan;44(1):1-10. Review.

3.

Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.

Lu H, Tonge PJ.

Acc Chem Res. 2008 Jan;41(1):11-20. doi: 10.1021/ar700156e. Review.

PMID:
18193820
4.

Lipid biosynthesis as a target for antibacterial agents.

Heath RJ, White SW, Rock CO.

Prog Lipid Res. 2001 Nov;40(6):467-97. Review.

PMID:
11591436
5.

Regulation of fatty acid metabolism in bacteria.

Fujita Y, Matsuoka H, Hirooka K.

Mol Microbiol. 2007 Nov;66(4):829-39. Epub 2007 Oct 2. Review.

6.

Current understanding of fatty acid biosynthesis and the acyl carrier protein.

Chan DI, Vogel HJ.

Biochem J. 2010 Aug 15;430(1):1-19. doi: 10.1042/BJ20100462. Review. Erratum in: Biochem J. 2010 Aug 27;430(3):559.

PMID:
20662770
7.

Product diversity and regulation of type II fatty acid synthases.

Lu YJ, Zhang YM, Rock CO.

Biochem Cell Biol. 2004 Feb;82(1):145-55. Review.

PMID:
15052334
8.

Acyl carrier protein: structure-function relationships in a conserved multifunctional protein family.

Byers DM, Gong H.

Biochem Cell Biol. 2007 Dec;85(6):649-62. Review.

PMID:
18059524
9.

Inhibiting bacterial fatty acid synthesis.

Zhang YM, White SW, Rock CO.

J Biol Chem. 2006 Jun 30;281(26):17541-4. Epub 2006 Apr 28. Review.

10.

Fatty Acid synthesis as a target for antimalarial drug discovery.

Lu JZ, Lee PJ, Waters NC, Prigge ST.

Comb Chem High Throughput Screen. 2005 Feb;8(1):15-26. Review.

PMID:
15720194
11.

Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex.

Oliveira JS, de Sousa EH, de Souza ON, Moreira IS, Santos DS, Basso LA.

Curr Pharm Des. 2006;12(19):2409-24. Review.

PMID:
16842188
12.

The reductase steps of the type II fatty acid synthase as antimicrobial targets.

Zhang YM, Lu YJ, Rock CO.

Lipids. 2004 Nov;39(11):1055-60. Review.

PMID:
15726819
13.

Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics.

Heath RJ, White SW, Rock CO.

Appl Microbiol Biotechnol. 2002 May;58(6):695-703. Epub 2002 Mar 7. Review.

PMID:
12021787
14.

The structural biology of type II fatty acid biosynthesis.

White SW, Zheng J, Zhang YM, Rock.

Annu Rev Biochem. 2005;74:791-831. Review.

PMID:
15952903
15.

Identification of inhibitors of bacterial enoyl-acyl carrier protein reductase.

Moir DT.

Curr Drug Targets Infect Disord. 2005 Sep;5(3):297-305. Review.

PMID:
16181147
16.

Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents.

Oliveira JS, Vasconcelos IB, Moreira IS, Santos DS, Basso LA.

Curr Drug Targets. 2007 Mar;8(3):399-411. Review.

PMID:
17348833
17.

Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.

Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ.

Prog Lipid Res. 2010 Jan;49(1):27-45. doi: 10.1016/j.plipres.2009.08.001. Epub 2009 Aug 15. Review.

PMID:
19686777
18.

Structural and functional organization of the animal fatty acid synthase.

Smith S, Witkowski A, Joshi AK.

Prog Lipid Res. 2003 Jul;42(4):289-317. Review.

PMID:
12689621
19.
20.

Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.

Wang Y, Ma S.

ChemMedChem. 2013 Oct;8(10):1589-608. doi: 10.1002/cmdc.201300209. Epub 2013 Jul 24. Review.

PMID:
23894064

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