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Items: 1 to 20 of 56

1.

Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease.

Cruts M, Dermaut B, Rademakers R, Roks G, Van den Broeck M, Munteanu G, van Duijn CM, Van Broeckhoven C.

Neurosci Lett. 2001 Nov 2;313(1-2):105-7.

PMID:
11684351
2.

The beta-secretase, BACE: a prime drug target for Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2001 Oct;17(2):157-70. Review.

PMID:
11816789
3.
4.

BACE1: the beta-secretase enzyme in Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2004;23(1-2):105-14. Review.

PMID:
15126696
5.

Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.

Johnston JA, Liu WW, Todd SA, Coulson DT, Murphy S, Irvine GB, Passmore AP.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1096-100. Review.

PMID:
16246054
6.

Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Vassar R.

Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602. Review.

PMID:
12453676
7.

Human beta-secretase (BACE) and BACE inhibitors: progress report.

John V.

Curr Top Med Chem. 2006;6(6):569-78. Review.

PMID:
16712492
8.

The molecular link between beta- and gamma-secretase activity on the amyloid beta precursor protein.

Tabaton M, Tamagno E.

Cell Mol Life Sci. 2007 Sep;64(17):2211-8. Review.

PMID:
17604999
10.

Uncovering gamma-secretase.

Steiner H.

Curr Alzheimer Res. 2004 Aug;1(3):175-81. Review.

PMID:
15975065
11.

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

Stockley JH, O'Neill C.

Biochem Soc Trans. 2007 Jun;35(Pt 3):574-6. Review.

PMID:
17511655
12.

beta-Secretase, APP and Abeta in Alzheimer's disease.

Vassar R.

Subcell Biochem. 2005;38:79-103. Review.

PMID:
15709474
13.
14.

Regulation of APP cleavage by alpha-, beta- and gamma-secretases.

Nunan J, Small DH.

FEBS Lett. 2000 Oct 13;483(1):6-10. Review.

15.

APP, Notch, and presenilin: molecular pieces in the puzzle of Alzheimer's disease.

Wolfe MS.

Int Immunopharmacol. 2002 Dec;2(13-14):1919-29. Review.

PMID:
12489805
17.
18.

BACE1 structure and function in health and Alzheimer's disease.

Cole SL, Vassar R.

Curr Alzheimer Res. 2008 Apr;5(2):100-20. Review.

PMID:
18393796
19.

Progress in the development of nonpeptidomimetic BACE 1 inhibitors for Alzheimer's disease.

Huang WH, Sheng R, Hu YZ.

Curr Med Chem. 2009;16(14):1806-20. Review.

PMID:
19442147
20.

The search for gamma-secretase and development of inhibitors.

Tsai JY, Wolfe MS, Xia W.

Curr Med Chem. 2002 Jun;9(11):1087-106. Review.

PMID:
12052174

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