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Biochem Soc Trans. 2001 Aug;29(Pt 4):418-21.

Incorporation of iron-sulphur clusters in membrane-bound proteins.

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  • 1Department of Plant Biochemistry, Faculty of Biology, Ruhr-University Bochum, Germany.


The completely sequenced genome of the cyanobacterium Synechocystis PCC 6803 contains several open reading frames, of which the deduced amino acid sequences show similarities to proteins known to be involved in FeS cluster synthesis of nitrogenase (Nif proteins) and other FeS proteins (Isc proteins). In this article, the results of our studies on these proteins are summarized and discussed with respect to their relevance in FeS cluster incorporation in chloroplasts. In cyanobacteria, there appears to exist several pathways for FeS cluster synthesis.

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