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Items: 15

1.

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch.

Ray WJ, Yao M, Mumm J, Schroeter EH, Saftig P, Wolfe M, Selkoe DJ, Kopan R, Goate AM.

J Biol Chem. 1999 Dec 17;274(51):36801-7.

2.

Role of presenilin in gamma-secretase cleavage of amyloid precursor protein.

Xia W.

Exp Gerontol. 2000 Jul;35(4):453-60. Review.

PMID:
10959033
3.

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C.

Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. Review.

PMID:
10653281
5.

APP, Notch, and presenilin: molecular pieces in the puzzle of Alzheimer's disease.

Wolfe MS.

Int Immunopharmacol. 2002 Dec;2(13-14):1919-29. Review.

PMID:
12489805
6.

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease.

Selkoe DJ.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11039-41. Review.

7.

Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease.

Wolfe MS, De Los Angeles J, Miller DD, Xia W, Selkoe DJ.

Biochemistry. 1999 Aug 31;38(35):11223-30. Review.

PMID:
10471271
8.

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

Selkoe D, Kopan R.

Annu Rev Neurosci. 2003;26:565-97. Epub 2003 Apr 18. Review.

PMID:
12730322
9.

Implication of APP secretases in notch signaling.

Hartmann D, Tournoy J, Saftig P, Annaert W, De Strooper B.

J Mol Neurosci. 2001 Oct;17(2):171-81. Review.

PMID:
11816790
10.
11.

Presenilins: molecular switches between proteolysis and signal transduction.

Annaert W, De Strooper B.

Trends Neurosci. 1999 Oct;22(10):439-43. Review.

PMID:
10481190
12.
13.

Notch receptors, partners and regulators: from conserved domains to powerful functions.

Egan SE, St-Pierre B, Leow CC.

Curr Top Microbiol Immunol. 1998;228:273-324. Review. No abstract available.

PMID:
9401210
14.

[Site-2 protease: a protein that catalyzes the regulated intramembrane proteolysis of SREBPs].

Sakai J.

Nihon Rinsho. 2001 Feb;59 Suppl 2:283-7. Review. Japanese. No abstract available.

PMID:
11351589
15.

Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins.

Ehlers MR, Riordan JF.

Biochemistry. 1991 Oct 22;30(42):10065-74. Review. No abstract available.

PMID:
1931937

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