Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 8

1.

Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).

Balzarini J, Naesens L, Aquaro S, Knispel T, Perno C, De Clercq E, Meier C.

Mol Pharmacol. 1999 Dec;56(6):1354-61.

2.

Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).

Parang K, Wiebe LI, Knaus EE.

Curr Med Chem. 2000 Oct;7(10):995-1039. Review.

3.

Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase.

Lavie A, Konrad M.

Mini Rev Med Chem. 2004 May;4(4):351-9. Review.

PMID:
15134538
4.

AZT: an old drug with new perspectives.

D'Andrea G, Brisdelli F, Bozzi A.

Curr Clin Pharmacol. 2008 Jan;3(1):20-37. Review.

PMID:
18690875
5.

Anti-HIV therapy with AZT prodrugs: AZT phosphonate derivatives, current state and prospects.

Khandazhinskaya A, Matyugina E, Shirokova E.

Expert Opin Drug Metab Toxicol. 2010 Jun;6(6):701-14. doi: 10.1517/17425251003713501. Review.

PMID:
20380483
6.

Rational Development of Nucleoside Diphosphate Prodrugs: DiPPro-Compounds.

Meier C, Jessen HJ, Schulz T, Weinschenk L, Pertenbreiter F, Balzarini J.

Curr Med Chem. 2015;22(34):3933-50. Review.

PMID:
26303175
7.

Effects of AZT on cellular iron homeostasis.

Bozzi A, Brisdelli F, D'Alessandro AM, D'Andrea G, Lizzi AR, Rinaldi AC, Oratore A.

Biometals. 2004 Aug;17(4):443-50. Review.

PMID:
15259365
8.

Recent progress in prodrug design strategies based on generally applicable modifications.

Hamada Y.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1627-1632. doi: 10.1016/j.bmcl.2017.02.075. Epub 2017 Mar 2. Review.

PMID:
28285913

Supplemental Content

Support Center