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Items: 1 to 20 of 342

1.

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

Itoh M, Takahashi T, Sakaguchi N, Kuniyasu Y, Shimizu J, Otsuka F, Sakaguchi S.

J Immunol. 1999 May 1;162(9):5317-26.

2.

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance.

Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M, Takahashi T.

Immunol Rev. 2001 Aug;182:18-32. Review.

PMID:
11722621
3.

Thymic regulatory T cells.

Maggi E, Cosmi L, Liotta F, Romagnani P, Romagnani S, Annunziato F.

Autoimmun Rev. 2005 Nov;4(8):579-86. Review.

PMID:
16214099
4.

Control of T-cell activation by CD4+ CD25+ suppressor T cells.

Shevach EM, McHugh RS, Piccirillo CA, Thornton AM.

Immunol Rev. 2001 Aug;182:58-67. Review.

PMID:
11722623
5.

Interleukin-2 signaling and the maintenance of self-tolerance.

Nelson BH.

Curr Dir Autoimmun. 2002;5:92-112. Review.

PMID:
11826762
6.

Interleukin-2, a pro-autoimmune lymphokine that interferes with post-deletional tolerance.

Kroemer G, Martínez C.

Semin Immunol. 1992 Jun;4(3):167-79. Review.

PMID:
1627788
7.

The development of functionally responsive T cells.

Rothenberg EV.

Adv Immunol. 1992;51:85-214. Review.

PMID:
1386962
8.

Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease.

Sakaguchi S, Ono M, Setoguchi R, Yagi H, Hori S, Fehervari Z, Shimizu J, Takahashi T, Nomura T.

Immunol Rev. 2006 Aug;212:8-27. Review.

PMID:
16903903
9.

Thymic involution: implications for self-tolerance.

Hakim FT, Gress RE.

Methods Mol Biol. 2007;380:377-90. Review.

PMID:
17876107
10.

The generation and antigen-specificity of CD4+CD25+ regulatory T cells.

Taams LS, Curnow SJ, Vukmanovic-Stejic M, Akbar AN.

Inflamm Allergy Drug Targets. 2006 Sep;5(3):149-56. Review.

PMID:
16918478
11.

Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.

Coutinho A, Caramalho I, Seixas E, Demengeot J.

Curr Top Microbiol Immunol. 2005;293:43-71. Review.

PMID:
15981475
12.

Defective clonal deletion and anergy induction in TCR transgenic lpr/lpr mice.

Mountz JD, Bluethmann H, Zhou T, Wu J.

Semin Immunol. 1994 Feb;6(1):27-37. Review.

PMID:
8167304
13.

Apoptosis defects analyzed in TcR transgenic and fas transgenic lpr mice.

Mountz JD, Zhou T, Bluethmann H, Wu J, Edwards CK 3rd.

Int Rev Immunol. 1994;11(4):321-42. Review.

PMID:
7528763
14.

Gld and lpr mice: single gene mutant models for failed self tolerance.

Bhandoola A, Yui K, Siegel RM, Zerva L, Greene MI.

Int Rev Immunol. 1994;11(3):231-44. Review.

PMID:
7930847
15.

Intrathymic activation events and the generation of IL-4 producer CD4+8- thymocytes.

Bendelac A.

Semin Immunol. 1992 Jun;4(3):187-93. Review.

PMID:
1352709
16.

The generation and fate of thymocytes.

Shortman K, Egerton M, Spangrude GJ, Scollay R.

Semin Immunol. 1990 Jan;2(1):3-12. Review.

PMID:
2129900
17.
18.

Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells.

Le Douarin N, Corbel C, Bandeira A, Thomas-Vaslin V, Modigliani Y, Coutinho A, Salaün J.

Immunol Rev. 1996 Feb;149:35-53. Review.

PMID:
9005218
19.

Regulatory T cells: roles of T cell receptor for their development and function.

Ohkura N, Sakaguchi S.

Semin Immunopathol. 2010 Jun;32(2):95-106. doi: 10.1007/s00281-010-0200-5. Epub 2010 Feb 24. Review.

PMID:
20179931
20.

Mechanisms of autoimmunity in the context of T-cell tolerance: insights from natural and transgenic animal model systems.

Siegel RM, Katsumata M, Komori S, Wadsworth S, Gill-Morse L, Jerrold-Jones S, Bhandoola A, Greene MI, Yui K.

Immunol Rev. 1990 Dec;118:165-92. Review.

PMID:
2150401

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