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Items: 1 to 20 of 30

1.

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, BrĂ¼ning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR.

Cell. 1999 Feb 5;96(3):329-39.

2.
4.

Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance.

Mauvais-Jarvis F, Kulkarni RN, Kahn CR.

Clin Endocrinol (Oxf). 2002 Jul;57(1):1-9. Review.

PMID:
12100063
5.

The Cre-loxP system: a versatile tool for targeting genes in a cell- and stage-specific manner.

Ray MK, Fagan SP, Brunicardi FC.

Cell Transplant. 2000 Nov-Dec;9(6):805-15. Review.

PMID:
11202567
6.

Secretion of glycated insulin from pancreatic beta-cells in diabetes represents a novel aspect of beta-cell dysfunction and glucose toxicity.

McKillop AM, Abdel-Wahab YH, Mooney MH, O'Harte FP, Flatt PR.

Diabetes Metab. 2002 Dec;28(6 Pt 2):3S61-9; discussion 3S108-12. Review.

PMID:
12688635
7.

Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus.

Kahn CR, BrĂ¼ning JC, Michael MD, Kulkarni RN.

J Pediatr Endocrinol Metab. 2000;13 Suppl 6:1377-84. Review.

PMID:
11202213
8.

Cell-specific roles of glucokinase in glucose homeostasis.

Postic C, Shiota M, Magnuson MA.

Recent Prog Horm Res. 2001;56:195-217. Review.

PMID:
11237213
9.

Molecular insights into insulin action and secretion.

Rhodes CJ, White MF.

Eur J Clin Invest. 2002 Jun;32 Suppl 3:3-13. Review.

PMID:
12028370
10.

Beta- and alpha-cell dysfunction in type 2 diabetes.

Del Prato S, Marchetti P.

Horm Metab Res. 2004 Nov-Dec;36(11-12):775-81. Review.

PMID:
15655708
11.

In vivo mutagenesis of the insulin receptor.

Okamoto H, Accili D.

J Biol Chem. 2003 Aug 1;278(31):28359-62. Epub 2003 Jun 4. Review.

12.

Pathogenesis of NIDDM--a disease of deficient insulin secretion.

Turner RC, Matthews DR, Clark A, O'Rahilly S, Rudenski AS, Levy J.

Baillieres Clin Endocrinol Metab. 1988 May;2(2):327-42. Review.

PMID:
3075895
13.

[Relative importance of insulin actin in insulin's target tissues].

Sasaoka T, Kobayashi M.

Nihon Rinsho. 2000 Feb;58(2):291-6. Review. Japanese.

PMID:
10707547
14.

[Diabetogenes; which cause type II diabetes mellitus].

Murakami T, Shima K.

Rinsho Byori. 1995 Aug;43(8):781-5. Review. Japanese.

PMID:
7474436
15.

Pancreatic beta-cells: Role of glycerol and aquaglyceroporin 7.

Virreira M, Perret J, Delporte C.

Int J Biochem Cell Biol. 2011 Jan;43(1):10-3. doi: 10.1016/j.biocel.2010.10.018. Epub 2010 Nov 5. Review.

PMID:
21056684
16.

[Knockout mouse models for type 2 diabetes. Mice with impaired insulin secretion].

Terauchi Y, Kadowaki T.

Nihon Rinsho. 2002 Aug;60 Suppl 8:58-63. Review. Japanese. No abstract available.

PMID:
12355812
17.

[Biochemical bases of abnormalities of glucose metabolism in non-insulin-dependent diabetes].

Girard J.

Journ Annu Diabetol Hotel Dieu. 1993:81-96. Review. French. No abstract available.

PMID:
8392644
18.

Pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes.

Flatt PR, Abdel-Wahab YH, Boyd AC, Barnett CR, O'Harte FP.

Proc Nutr Soc. 1997 Mar;56(1B):243-62. Review. No abstract available.

PMID:
9168536
19.

[Molecular biology and clinical diabetology].

Kasuga M.

Nihon Rinsho. 1999 Mar;57(3):497-502. Review. Japanese.

PMID:
10199124
20.

Tissue-specific targeting of the insulin receptor gene.

Kulkarni RN, Okada T.

Endocrine. 2002 Dec;19(3):257-66. Review.

PMID:
12624425

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