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Items: 13


Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective.

Krishna KH, Vadlamudi Y, Kumar MS.

PLoS One. 2016 Apr 18;11(4):e0153680. doi: 10.1371/journal.pone.0153680. eCollection 2016.


The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.

Ogolla PS, Portillo JA, White CL, Patel K, Lamb B, Sen GC, Subauste CS.

PLoS Pathog. 2013;9(8):e1003557. doi: 10.1371/journal.ppat.1003557. Epub 2013 Aug 22.


Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action.

GarcĂ­a MA, Gil J, Ventoso I, Guerra S, Domingo E, Rivas C, Esteban M.

Microbiol Mol Biol Rev. 2006 Dec;70(4):1032-60. Review.


RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection.

Bennett RL, Blalock WL, Abtahi DM, Pan Y, Moyer SA, May WS.

Blood. 2006 Aug 1;108(3):821-9.


TNF-alpha sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis.

Frankel SK, Cosgrove GP, Cha SI, Cool CD, Wynes MW, Edelman BL, Brown KK, Riches DW.

Am J Respir Cell Mol Biol. 2006 Mar;34(3):293-304. Epub 2005 Nov 4.


Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.

Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D.

Mol Cell Biol. 2004 Dec;24(23):10161-8.


Transfection of single-stranded hepatitis A virus RNA activates MHC class I pathway.

Suzuki K, Yanagi M, Mori-Aoki A, Moriyama E, Ishii KJ, Kohn LD.

Clin Exp Immunol. 2002 Feb;127(2):234-42.

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