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Items: 1 to 20 of 33


Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.

Voisinne G, García-Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, Malissen M, Burlet-Schiltz O, Gonzalez de Peredo A, Malissen B, Roncagalli R.

Mol Syst Biol. 2016 Jul 29;12(7):876. doi: 10.15252/msb.20166837.


Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.

Scanlon V, Soung do Y, Adapala NS, Morgan E, Hansen MF, Drissi H, Sanjay A.

PLoS One. 2015 Sep 22;10(9):e0138194. doi: 10.1371/journal.pone.0138194. eCollection 2015.


Mutations of c-Cbl in myeloid malignancies.

Katzav S, Schmitz ML.

Oncotarget. 2015 May 10;6(13):10689-96. Review.


Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.

Adapala NS, Holland D, Scanlon V, Barbe MF, Langdon WY, Tsygankov AY, Lorenzo JA, Sanjay A.

Bone. 2014 Oct;67:1-9. doi: 10.1016/j.bone.2014.06.013. Epub 2014 Jul 1.


E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.

Liu Q, Zhou H, Langdon WY, Zhang J.

Cell Cycle. 2014;13(12):1875-84. doi: 10.4161/cc.29213. Epub 2014 May 14. Review.


Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.

Adapala NS, Barbe MF, Tsygankov AY, Lorenzo JA, Sanjay A.

J Cell Biochem. 2014 Jul;115(7):1277-89. doi: 10.1002/jcb.24779.


Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.

Bulut GB, Sulahian R, Yao H, Huang LJ.

Blood. 2013 Dec 5;122(24):3964-72. doi: 10.1182/blood-2013-05-506212. Epub 2013 Oct 10.


Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.

Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N.

Nat Med. 2013 May;19(5):586-94. doi: 10.1038/nm.3150. Epub 2013 Apr 14.


E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis.

Sévère N, Dieudonné FX, Marie PJ.

Cell Death Dis. 2013 Jan 17;4:e463. doi: 10.1038/cddis.2012.217. Review.


SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

Liu BA, Engelmann BW, Jablonowski K, Higginbotham K, Stergachis AB, Nash PD.

Cell Commun Signal. 2012 Sep 14;10(1):27. doi: 10.1186/1478-811X-10-27.


Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.

Hatton O, Lambert SL, Krams SM, Martinez OM.

PLoS One. 2012;7(8):e42610. doi: 10.1371/journal.pone.0042610. Epub 2012 Aug 3.


Anergy in CD4 memory T lymphocytes. II. Abrogation of TCR-induced formation of membrane signaling complexes.

Lee WT, Prasad A, Watson AR.

Cell Immunol. 2012 Mar-Apr;276(1-2):26-34. doi: 10.1016/j.cellimm.2012.05.007. Epub 2012 May 19.


Superantigen-induced CD4 memory T cell anergy. I. Staphylococcal enterotoxin B induces Fyn-mediated negative signaling.

Watson AR, Janik DK, Lee WT.

Cell Immunol. 2012 Mar-Apr;276(1-2):16-25. doi: 10.1016/j.cellimm.2012.02.003. Epub 2012 Feb 17.


Identification of components of the host type IA phosphoinositide 3-kinase pathway that promote internalization of Listeria monocytogenes.

Jiwani S, Wang Y, Dowd GC, Gianfelice A, Pichestapong P, Gavicherla B, Vanbennekom N, Ireton K.

Infect Immun. 2012 Mar;80(3):1252-66. doi: 10.1128/IAI.06082-11. Epub 2011 Dec 12.


Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.

Buitrago L, Langdon WY, Sanjay A, Kunapuli SP.

Blood. 2011 Nov 17;118(20):5631-40. doi: 10.1182/blood-2011-01-328807. Epub 2011 Oct 3.


Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation.

Brennan T, Adapala NS, Barbe MF, Yingling V, Sanjay A.

Calcif Tissue Int. 2011 Nov;89(5):396-410. doi: 10.1007/s00223-011-9531-z. Epub 2011 Sep 28.


The E3 ligase c-Cbl regulates dendritic cell activation.

Chiou SH, Shahi P, Wagner RT, Hu H, Lapteva N, Seethammagari M, Sun SC, Levitt JM, Spencer DM.

EMBO Rep. 2011 Sep 1;12(9):971-9. doi: 10.1038/embor.2011.143.


Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance.

Yamada E, Lee TW, Pessin JE, Bastie CC.

Future Med Chem. 2010 Dec;2(12):1785-96. doi: 10.4155/fmc.10.264. Review.


The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.

Adapala NS, Barbe MF, Langdon WY, Nakamura MC, Tsygankov AY, Sanjay A.

J Biol Chem. 2010 Nov 19;285(47):36745-58. doi: 10.1074/jbc.M110.124628. Epub 2010 Sep 17.

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