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Items: 1 to 20 of 56


Achondroplasia: Development, pathogenesis, and therapy.

Ornitz DM, Legeai-Mallet L.

Dev Dyn. 2017 Apr;246(4):291-309. doi: 10.1002/dvdy.24479. Epub 2017 Mar 2. Review.


Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis.

Wen X, Li X, Tang Y, Tang J, Zhou S, Xie Y, Guo J, Yang J, Du X, Su N, Chen L.

J Biol Chem. 2016 Nov 25;291(48):24912-24921. Epub 2016 Oct 11.


A Track Record on SHOX: From Basic Research to Complex Models and Therapy.

Marchini A, Ogata T, Rappold GA.

Endocr Rev. 2016 Aug;37(4):417-48. doi: 10.1210/er.2016-1036. Epub 2016 Jun 29.


Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling.

Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD.

Bone. 2016 Jul;88:170-9. doi: 10.1016/j.bone.2016.04.023. Epub 2016 Apr 26.


Genetic insights into the mechanisms of Fgf signaling.

Brewer JR, Mazot P, Soriano P.

Genes Dev. 2016 Apr 1;30(7):751-71. doi: 10.1101/gad.277137.115. Review.


Antitumor effects and molecular mechanisms of ponatinib on endometrial cancer cells harboring activating FGFR2 mutations.

Kim DH, Kwak Y, Kim ND, Sim T.

Cancer Biol Ther. 2016;17(1):65-78. doi: 10.1080/15384047.2015.1108492.


Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up.

Roselló-Díez A, Joyner AL.

Endocr Rev. 2015 Dec;36(6):646-80. doi: 10.1210/er.2015-1048. Epub 2015 Oct 20. Review.


Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.

Su N, Jin M, Chen L.

Bone Res. 2014 Apr 29;2:14003. doi: 10.1038/boneres.2014.3. eCollection 2014. Review.


FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.

Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L.

PLoS Genet. 2015 Jun 19;11(6):e1005214. doi: 10.1371/journal.pgen.1005214. eCollection 2015 Jun.


Micro CT Analysis of Spine Architecture in a Mouse Model of Scoliosis.

Gao C, Chen BP, Sullivan MB, Hui J, Ouellet JA, Henderson JE, Saran N.

Front Endocrinol (Lausanne). 2015 Mar 19;6:38. doi: 10.3389/fendo.2015.00038. eCollection 2015.


The Fibroblast Growth Factor signaling pathway.

Ornitz DM, Itoh N.

Wiley Interdiscip Rev Dev Biol. 2015 May-Jun;4(3):215-66. doi: 10.1002/wdev.176. Epub 2015 Mar 13. Review.


FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.

Karolak MR, Yang X, Elefteriou F.

Hum Mol Genet. 2015 May 1;24(9):2552-64. doi: 10.1093/hmg/ddv019. Epub 2015 Jan 23.


Twist1- and Twist2-haploinsufficiency results in reduced bone formation.

Huang Y, Meng T, Wang S, Zhang H, Mues G, Qin C, Feng JQ, D'Souza RN, Lu Y.

PLoS One. 2014 Jun 27;9(6):e99331. doi: 10.1371/journal.pone.0099331. eCollection 2014.


Recent research on the growth plate: Recent insights into the regulation of the growth plate.

Lui JC, Nilsson O, Baron J.

J Mol Endocrinol. 2014 Aug;53(1):T1-9. doi: 10.1530/JME-14-0022. Epub 2014 Apr 16. Review.


FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.

Qi H, Jin M, Duan Y, Du X, Zhang Y, Ren F, Wang Y, Tian Q, Wang X, Wang Q, Zhu Y, Xie Y, Liu C, Cao X, Mishina Y, Chen D, Deng CX, Chang Z, Chen L.

Biochim Biophys Acta. 2014 Jul;1843(7):1237-47. doi: 10.1016/j.bbamcr.2014.03.011. Epub 2014 Mar 20.


Current understanding on the molecular basis of chondrogenesis.

Michigami T.

Clin Pediatr Endocrinol. 2014 Jan;23(1):1-8. doi: 10.1292/cpe.23.1. Epub 2014 Feb 3. Review.


Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer.

Turkington RC, Longley DB, Allen WL, Stevenson L, McLaughlin K, Dunne PD, Blayney JK, Salto-Tellez M, Van Schaeybroeck S, Johnston PG.

Cell Death Dis. 2014 Feb 6;5:e1046. doi: 10.1038/cddis.2014.10.


A Ser252Trp mutation in fibroblast growth factor receptor 2 (FGFR2) mimicking human Apert syndrome reveals an essential role for FGF signaling in the regulation of endochondral bone formation.

Chen P, Zhang L, Weng T, Zhang S, Sun S, Chang M, Li Y, Zhang B, Zhang L.

PLoS One. 2014 Jan 28;9(1):e87311. doi: 10.1371/journal.pone.0087311. eCollection 2014.


FGFR3 has tumor suppressor properties in cells with epithelial phenotype.

Lafitte M, Moranvillier I, Garcia S, Peuchant E, Iovanna J, Rousseau B, Dubus P, Guyonnet-Dupérat V, Belleannée G, Ramos J, Bedel A, de Verneuil H, Moreau-Gaudry F, Dabernat S.

Mol Cancer. 2013 Jul 31;12:83. doi: 10.1186/1476-4598-12-83.


Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers.

Tiong KH, Mah LY, Leong CO.

Apoptosis. 2013 Dec;18(12):1447-68. doi: 10.1007/s10495-013-0886-7. Review.

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