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Items: 1 to 20 of 74


Hidden Structural Modules in a Cooperative RNA Folding Transition.

Gracia B, Al-Hashimi HM, Bisaria N, Das R, Herschlag D, Russell R.

Cell Rep. 2018 Mar 20;22(12):3240-3250. doi: 10.1016/j.celrep.2018.02.101.


Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.

Ray S, Widom JR, Walter NG.

Chem Rev. 2018 Apr 25;118(8):4120-4155. doi: 10.1021/acs.chemrev.7b00519. Epub 2018 Jan 24.


Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs.

Sloma MF, Mathews DH.

PLoS Comput Biol. 2017 Nov 6;13(11):e1005827. doi: 10.1371/journal.pcbi.1005827. eCollection 2017 Nov.


RNA Structural Modules Control the Rate and Pathway of RNA Folding and Assembly.

Gracia B, Xue Y, Bisaria N, Herschlag D, Al-Hashimi HM, Russell R.

J Mol Biol. 2016 Oct 9;428(20):3972-3985. doi: 10.1016/j.jmb.2016.07.013. Epub 2016 Jul 22.


Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch.

Xue Y, Gracia B, Herschlag D, Russell R, Al-Hashimi HM.

Nat Commun. 2016 Jun 13;7:ncomms11768. doi: 10.1038/ncomms11768.


Structural Divergence of the Group I Intron Binding Surface in Fungal Mitochondrial Tyrosyl-tRNA Synthetases That Function in RNA Splicing.

Lamech LT, Saoji M, Paukstelis PJ, Lambowitz AM.

J Biol Chem. 2016 May 27;291(22):11911-27. doi: 10.1074/jbc.M116.725390. Epub 2016 Apr 1.


An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.

Sengupta RN, Van Schie SN, Giambaşu G, Dai Q, Yesselman JD, York D, Piccirilli JA, Herschlag D.

RNA. 2016 Jan;22(1):32-48. doi: 10.1261/rna.053710.115. Epub 2015 Nov 13.


Exploiting post-transcriptional regulation to probe RNA structures in vivo via fluorescence.

Sowa SW, Vazquez-Anderson J, Clark CA, De La Peña R, Dunn K, Fung EK, Khoury MJ, Contreras LM.

Nucleic Acids Res. 2015 Jan;43(2):e13. doi: 10.1093/nar/gku1191. Epub 2014 Nov 21.


RNA tertiary structure analysis by 2'-hydroxyl molecular interference.

Homan PJ, Tandon A, Rice GM, Ding F, Dokholyan NV, Weeks KM.

Biochemistry. 2014 Nov 4;53(43):6825-33. doi: 10.1021/bi501218g. Epub 2014 Oct 23.


DEAD-box protein CYT-19 is activated by exposed helices in a group I intron RNA.

Jarmoskaite I, Bhaskaran H, Seifert S, Russell R.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2928-36. doi: 10.1073/pnas.1404307111. Epub 2014 Jul 7.


Roles of long-range tertiary interactions in limiting dynamics of the Tetrahymena group I ribozyme.

Shi X, Bisaria N, Benz-Moy TL, Bonilla S, Pavlichin DS, Herschlag D.

J Am Chem Soc. 2014 May 7;136(18):6643-8. doi: 10.1021/ja413033d. Epub 2014 Apr 28.


Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic model.

Huet T, Miannay FA, Patton JR, Thore S.

PLoS One. 2014 Apr 10;9(4):e94610. doi: 10.1371/journal.pone.0094610. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0122147.


RNA synthesis and purification for structural studies.

Ahmed YL, Ficner R.

RNA Biol. 2014;11(5):427-32. Epub 2014 Feb 10. Review.


Biophysical highlights from 54 years of macromolecular crystallography.

Richardson JS, Richardson DC.

Biophys J. 2014 Feb 4;106(3):510-25. doi: 10.1016/j.bpj.2014.01.001. Review.


The long-range P3 helix of the Tetrahymena ribozyme is disrupted during folding between the native and misfolded conformations.

Mitchell D 3rd, Jarmoskaite I, Seval N, Seifert S, Russell R.

J Mol Biol. 2013 Aug 9;425(15):2670-86. doi: 10.1016/j.jmb.2013.05.008. Epub 2013 May 20.


The right angle (RA) motif: a prevalent ribosomal RNA structural pattern found in group I introns.

Grabow WW, Zhuang Z, Swank ZN, Shea JE, Jaeger L.

J Mol Biol. 2012 Nov 23;424(1-2):54-67. doi: 10.1016/j.jmb.2012.09.012. Epub 2012 Sep 18.


Toward a molecular understanding of RNA remodeling by DEAD-box proteins.

Russell R, Jarmoskaite I, Lambowitz AM.

RNA Biol. 2013 Jan;10(1):44-55. doi: 10.4161/rna.22210. Epub 2012 Sep 20. Review.


A two-piece derivative of a group I intron RNA as a platform for designing self-assembling RNA templates to promote Peptide ligation.

Tanaka T, Furuta H, Ikawa Y.

J Nucleic Acids. 2012;2012:305867. doi: 10.1155/2012/305867. Epub 2012 Aug 22.


Enhanced specificity against misfolding in a thermostable mutant of the Tetrahymena ribozyme.

Wan Y, Russell R.

Biochemistry. 2011 Feb 8;50(5):864-74. doi: 10.1021/bi101467q. Epub 2011 Jan 11.


The Simbios National Center: Systems Biology in Motion.

Schmidt JP, Delp SL, Sherman MA, Taylor CA, Pande VS, Altman RB.

Proc IEEE Inst Electr Electron Eng. 2008 Aug 1;96(8):1266.

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