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Role of gabra2, GABAA receptor alpha-2 subunit, in CNS development.

Gonzalez-Nunez V.

Biochem Biophys Rep. 2015 Aug 6;3:190-201. doi: 10.1016/j.bbrep.2015.08.003. eCollection 2015 Sep.


The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus.

Albers HE, Walton JC, Gamble KL, McNeill JK 4th, Hummer DL.

Front Neuroendocrinol. 2017 Jan;44:35-82. doi: 10.1016/j.yfrne.2016.11.003. Epub 2016 Nov 25. Review.


Characterization of GABAA receptor ligands with automated patch-clamp using human neurons derived from pluripotent stem cells.

Yuan NY, Poe MM, Witzigmann C, Cook JM, Stafford D, Arnold LA.

J Pharmacol Toxicol Methods. 2016 Nov - Dec;82:109-114. doi: 10.1016/j.vascn.2016.08.006. Epub 2016 Aug 18.


Drug Development in Alzheimer's Disease: The Contribution of PET and SPECT.

Declercq LD, Vandenberghe R, Van Laere K, Verbruggen A, Bormans G.

Front Pharmacol. 2016 Mar 31;7:88. doi: 10.3389/fphar.2016.00088. eCollection 2016. Review.


Current and Future Issues in the Development of Spinal Agents for the Management of Pain.

Yaksh TL, Fisher CJ, Hockman TM, Wiese AJ.

Curr Neuropharmacol. 2017;15(2):232-259. Review.


Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models.

Danhof M.

J Pharmacokinet Pharmacodyn. 2015 Oct;42(5):447-62. doi: 10.1007/s10928-015-9437-x. Epub 2015 Aug 30.


Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator.

Martin BS, Martinez-Botella G, Loya CM, Salituro FG, Robichaud AJ, Huntsman MM, Ackley MA, Doherty JJ, Corbin JG.

J Neurosci Res. 2016 Jun;94(6):568-78. doi: 10.1002/jnr.23632. Epub 2015 Aug 26.


GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures.

Lieberman R, Kranzler HR, Joshi P, Shin DG, Covault J.

Alcohol Clin Exp Res. 2015 Sep;39(9):1654-64. doi: 10.1111/acer.12807. Epub 2015 Aug 6.


Functional characterization of the 1,5-benzodiazepine clobazam and its major active metabolite N-desmethylclobazam at human GABA(A) receptors expressed in Xenopus laevis oocytes.

Hammer H, Ebert B, Jensen HS, Jensen AA.

PLoS One. 2015 Mar 23;10(3):e0120239. doi: 10.1371/journal.pone.0120239. eCollection 2015.


Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling.

Gallos G, Yocum GT, Siviski ME, Yim PD, Fu XW, Poe MM, Cook JM, Harrison N, Perez-Zoghbi J, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L931-42. doi: 10.1152/ajplung.00107.2014. Epub 2015 Feb 6.


Extrasynaptic α6 subunit-containing GABAA receptors modulate excitability in turtle spinal motoneurons.

Andres C, Aguilar J, González-Ramírez R, Elias-Viñas D, Felix R, Delgado-Lezama R.

PLoS One. 2014 Dec 22;9(12):e115378. doi: 10.1371/journal.pone.0115378. eCollection 2014.


Benzodiazepine-like discriminative stimulus effects of toluene vapor.

Shelton KL, Nicholson KL.

Eur J Pharmacol. 2013 Nov 15;720(1-3):131-7.


GABAergic dysfunction in pediatric neuro-developmental disorders.

Smith-Hicks CL.

Front Cell Neurosci. 2013 Dec 19;7:269. doi: 10.3389/fncel.2013.00269. Review.


Etomidate produces similar allosteric modulation in α1β3δ and α1β3γ2L GABA(A) receptors.

Feng HJ, Jounaidi Y, Haburcak M, Yang X, Forman SA.

Br J Pharmacol. 2014 Feb;171(3):789-98. doi: 10.1111/bph.12507.


The neurobiology of alcohol consumption and alcoholism: an integrative history.

Tabakoff B, Hoffman PL.

Pharmacol Biochem Behav. 2013 Nov 15;113:20-37. doi: 10.1016/j.pbb.2013.10.009. Epub 2013 Oct 17. Review.


Time-dependent modulation of GABA(A)-ergic synaptic transmission by allopregnanolone in locus coeruleus neurons of Mecp2-null mice.

Jin X, Zhong W, Jiang C.

Am J Physiol Cell Physiol. 2013 Dec 1;305(11):C1151-60. doi: 10.1152/ajpcell.00195.2013. Epub 2013 Sep 25.


Rethinking schizophrenia in the context of normal neurodevelopment.

Catts VS, Fung SJ, Long LE, Joshi D, Vercammen A, Allen KM, Fillman SG, Rothmond DA, Sinclair D, Tiwari Y, Tsai SY, Weickert TW, Shannon Weickert C.

Front Cell Neurosci. 2013 May 15;7:60. doi: 10.3389/fncel.2013.00060. eCollection 2013.


Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to α4 and γ2S mRNA levels respectively.

Verdurand M, Fillman SG, Weickert CS, Zavitsanou K.

PLoS One. 2013;8(1):e52724. doi: 10.1371/journal.pone.0052724. Epub 2013 Jan 8.

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