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Items: 11


The role of Tyk2 in regulation of breast cancer growth.

Zhang Q, Sturgill JL, Kmieciak M, Szczepanek K, Derecka M, Koebel C, Graham LJ, Dai Y, Chen S, Grant S, Cichy J, Shimoda K, Gamero A, Manjili M, Bear H, Conrad D, Larner AC.

J Interferon Cytokine Res. 2011 Sep;31(9):671-7. doi: 10.1089/jir.2011.0023. Epub 2011 Aug 24.


Jak/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies.

Jatiani SS, Baker SJ, Silverman LR, Reddy EP.

Genes Cancer. 2010 Oct;1(10):979-93. doi: 10.1177/1947601910397187.


TYK2 is a key regulator of the surveillance of B lymphoid tumors.

Stoiber D, Kovacic B, Schuster C, Schellack C, Karaghiosoff M, Kreibich R, Weisz E, Artwohl M, Kleine OC, Muller M, Baumgartner-Parzer S, Ghysdael J, Freissmuth M, Sexl V.

J Clin Invest. 2004 Dec;114(11):1650-8.


The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus.

Warren D, Griffin DS, Mainville C, Rosenberg N.

J Virol. 2003 Apr;77(8):4617-25.


Pim serine/threonine kinases regulate the stability of Socs-1 protein.

Chen XP, Losman JA, Cowan S, Donahue E, Fay S, Vuong BQ, Nawijn MC, Capece D, Cohan VL, Rothman P.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2175-80.


The carboxyl terminus of v-Abl protein can augment SH2 domain function.

Warren D, Heilpern AJ, Berg K, Rosenberg N.

J Virol. 2000 May;74(10):4495-504.


STAT signaling in the pathogenesis and treatment of cancer.

Frank DA.

Mol Med. 1999 Jul;5(7):432-56. Review.


Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis.

Nieborowska-Skorska M, Wasik MA, Slupianek A, Salomoni P, Kitamura T, Calabretta B, Skorski T.

J Exp Med. 1999 Apr 19;189(8):1229-42.

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