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Global DNA methylation and PTEN hypermethylation alterations in lung tissues from human silicosis.

Zhang X, Jia X, Mei L, Zheng M, Yu C, Ye M.

J Thorac Dis. 2016 Aug;8(8):2185-95. doi: 10.21037/jtd.2016.07.21.


Protein kinase C mechanisms that contribute to cardiac remodelling.

Newton AC, Antal CE, Steinberg SF.

Clin Sci (Lond). 2016 Sep 1;130(17):1499-510. doi: 10.1042/CS20160036. Review.


Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma.

Ali SA, Justilien V, Jamieson L, Murray NR, Fields AP.

Cancer Cell. 2016 Mar 14;29(3):367-78. doi: 10.1016/j.ccell.2016.02.012.


Capillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain Tissue.

Schrötter S, Leondaritis G, Eickholt BJ.

J Biol Chem. 2016 May 6;291(19):10239-51. doi: 10.1074/jbc.M115.700138. Epub 2016 Mar 4.


Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.

Das F, Ghosh-Choudhury N, Mariappan MM, Kasinath BS, Choudhury GG.

Am J Physiol Cell Physiol. 2016 Apr 1;310(7):C583-96. doi: 10.1152/ajpcell.00266.2015. Epub 2016 Jan 6.


PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions.

Gómez-Villafuertes R, García-Huerta P, Díaz-Hernández JI, Miras-Portugal MT.

Sci Rep. 2015 Dec 21;5:18417. doi: 10.1038/srep18417.


Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulation.

Tobias IS, Kaulich M, Kim PK, Simon N, Jacinto E, Dowdy SF, King CC, Newton AC.

Biochem J. 2016 Feb 15;473(4):509-23. doi: 10.1042/BJ20151013. Epub 2015 Dec 3.


Sequential posttranslational modifications regulate PKC degradation.

Wang Y, Wang Y, Zhang H, Gao Y, Huang C, Zhou A, Zhou Y, Li Y.

Mol Biol Cell. 2016 Jan 15;27(2):410-20. doi: 10.1091/mbc.E15-09-0624. Epub 2015 Nov 12.


Glutamine contributes to maintenance of mouse embryonic stem cell self-renewal through PKC-dependent downregulation of HDAC1 and DNMT1/3a.

Ryu JM, Lee SH, Seong JK, Han HJ.

Cell Cycle. 2015;14(20):3292-305. doi: 10.1080/15384101.2015.1087620.


Altering sphingolipid composition with aging induces contractile dysfunction of gastric smooth muscle via K(Ca) 1.1 upregulation.

Choi S, Kim JA, Kim TH, Li HY, Shin KO, Lee YM, Oh S, Pewzner-Jung Y, Futerman AH, Suh SH.

Aging Cell. 2015 Dec;14(6):982-94. doi: 10.1111/acel.12388. Epub 2015 Aug 20.


The Role of PKC-θ in CD4+ T Cells and HIV Infection: To the Nucleus and Back Again.

Phetsouphanh C, Kelleher AD.

Front Immunol. 2015 Jul 30;6:391. doi: 10.3389/fimmu.2015.00391. eCollection 2015. Review.


Hyperglycemia stimulates p62/PKCζ interaction, which mediates NF-κB activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscle.

Xi G, Shen X, Wai C, Vilas CK, Clemmons DR.

FASEB J. 2015 Dec;29(12):4772-82. doi: 10.1096/fj.15-275453. Epub 2015 Jul 31.


PKCι depletion initiates mitotic slippage-induced senescence in glioblastoma.

Restall IJ, Parolin DA, Daneshmand M, Hanson JE, Simard MA, Fitzpatrick ME, Kumar R, Lavictoire SJ, Lorimer IA.

Cell Cycle. 2015;14(18):2938-48. doi: 10.1080/15384101.2015.1071744.


The Novel PKCθ from Benchtop to Clinic.

Hage-Sleiman R, Hamze AB, Reslan L, Kobeissy H, Dbaibo G.

J Immunol Res. 2015;2015:348798. doi: 10.1155/2015/348798. Epub 2015 May 19. Review.


Threonine 34 phosphorylation by phosphoinositide-dependent protein kinase 1 facilitates dissociation of Akt from the plasma membrane.

Huang BX, Lee R, Akbar M, Kim HY.

Int J Biochem Cell Biol. 2015 Jul;64:195-201. doi: 10.1016/j.biocel.2015.04.007. Epub 2015 Apr 22.


Phosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.

Manna P, Jain SK.

Cell Physiol Biochem. 2015;35(4):1253-75. doi: 10.1159/000373949. Epub 2015 Feb 11. Review.


Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation.

Hsu WC, Nenov MN, Shavkunov A, Panova N, Zhan M, Laezza F.

PLoS One. 2015 Feb 6;10(2):e0117246. doi: 10.1371/journal.pone.0117246. eCollection 2015.



Anwer MS.

J Biosci (Rajshari). 2012;20:1-23.


Efficacy of dual PI-3K and mTOR inhibitors in vitro and in vivo in acute lymphoblastic leukemia.

Wong J, Welschinger R, Hewson J, Bradstock KF, Bendall LJ.

Oncotarget. 2014 Nov 15;5(21):10460-72.

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