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Items: 1 to 20 of 78

1.

Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers.

Rosholm KR, Baker MA, Ridone P, Nakayama Y, Rohde PR, Cuello LG, Lee LK, Martinac B.

Sci Rep. 2017 Mar 27;7:45180. doi: 10.1038/srep45180.

2.

Dynamics of Escherichia coli's passive response to a sudden decrease in external osmolarity.

Buda R, Liu Y, Yang J, Hegde S, Stevenson K, Bai F, Pilizota T.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5838-E5846. Epub 2016 Sep 19.

3.

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.

Bavi N, Cortes DM, Cox CD, Rohde PR, Liu W, Deitmer JW, Bavi O, Strop P, Hill AP, Rees D, Corry B, Perozo E, Martinac B.

Nat Commun. 2016 Jun 22;7:11984. doi: 10.1038/ncomms11984.

4.

Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore.

Wray R, Iscla I, Gao Y, Li H, Wang J, Blount P.

PLoS Biol. 2016 Jun 9;14(6):e1002473. doi: 10.1371/journal.pbio.1002473. eCollection 2016 Jun.

5.

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.

Iscla I, Wray R, Eaton C, Blount P.

PLoS One. 2015 Sep 14;10(9):e0137994. doi: 10.1371/journal.pone.0137994. eCollection 2015.

6.

Activation of bacterial channel MscL in mechanically stimulated droplet interface bilayers.

Najem JS, Dunlap MD, Rowe ID, Freeman EC, Grant JW, Sukharev S, Leo DJ.

Sci Rep. 2015 Sep 8;5:13726. doi: 10.1038/srep13726.

7.

Mutations in a Conserved Domain of E. coli MscS to the Most Conserved Superfamily Residue Leads to Kinetic Changes.

Malcolm HR, Blount P.

PLoS One. 2015 Sep 4;10(9):e0136756. doi: 10.1371/journal.pone.0136756. eCollection 2015.

8.

Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion.

Li J, Guo J, Ou X, Zhang M, Li Y, Liu Z.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10726-31. doi: 10.1073/pnas.1503202112. Epub 2015 Aug 10.

9.

Breaking the hydrophobicity of the MscL pore: insights into a charge-induced gating mechanism.

Chandramouli B, Di Maio D, Mancini G, Barone V, Brancato G.

PLoS One. 2015 Mar 31;10(3):e0120196. doi: 10.1371/journal.pone.0120196. eCollection 2015.

10.

The mechanosensitive channel of small conductance (MscS) functions as a Jack-in-the box.

Malcolm HR, Blount P, Maurer JA.

Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):159-66. doi: 10.1016/j.bbamem.2014.10.022. Epub 2014 Oct 23.

11.

Electrostatics at the membrane define MscL channel mechanosensitivity and kinetics.

Zhong D, Blount P.

FASEB J. 2014 Dec;28(12):5234-41. doi: 10.1096/fj.14-259309. Epub 2014 Sep 15.

12.

Streptomycin potency is dependent on MscL channel expression.

Iscla I, Wray R, Wei S, Posner B, Blount P.

Nat Commun. 2014 Sep 10;5:4891. doi: 10.1038/ncomms5891.

13.

Hydrophobic gating in ion channels.

Aryal P, Sansom MS, Tucker SJ.

J Mol Biol. 2015 Jan 16;427(1):121-30. doi: 10.1016/j.jmb.2014.07.030. Epub 2014 Aug 12. Review.

14.

The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating.

Mukherjee N, Jose MD, Birkner JP, Walko M, Ingólfsson HI, Dimitrova A, Arnarez C, Marrink SJ, Koçer A.

FASEB J. 2014 Oct;28(10):4292-302. doi: 10.1096/fj.14-251579. Epub 2014 Jun 23.

15.

MscL: channeling membrane tension.

Walton TA, Idigo CA, Herrera N, Rees DC.

Pflugers Arch. 2015 Jan;467(1):15-25. doi: 10.1007/s00424-014-1535-x. Epub 2014 May 27. Review.

16.

Dynamics of protein-protein interactions at the MscL periplasmic-lipid interface.

Zhong D, Yang LM, Blount P.

Biophys J. 2014 Jan 21;106(2):375-81. doi: 10.1016/j.bpj.2013.12.006.

17.

Structure and stability of the C-terminal helical bundle of the E. coli mechanosensitive channel of large conductance.

Walton TA, Rees DC.

Protein Sci. 2013 Nov;22(11):1592-601. doi: 10.1002/pro.2360. Epub 2013 Sep 30.

18.

Phosphatidylinositol is crucial for the mechanosensitivity of Mycobacterium tuberculosis MscL.

Zhong D, Blount P.

Biochemistry. 2013 Aug 13;52(32):5415-20. doi: 10.1021/bi400790j. Epub 2013 Aug 1.

19.

Inactivation of the bacterial RNA polymerase due to acquisition of secondary structure by the ω subunit.

Sarkar P, Sardesai AA, Murakami KS, Chatterji D.

J Biol Chem. 2013 Aug 30;288(35):25076-87. doi: 10.1074/jbc.M113.468520. Epub 2013 Jul 10.

20.

Characterization of the role of a mechanosensitive channel in osmotic down shock adaptation in Synechocystis sp PCC 6803.

Nanatani K, Shijuku T, Akai M, Yukutake Y, Yasui M, Hamamoto S, Onai K, Morishita M, Ishiura M, Uozumi N.

Channels (Austin). 2013 Jul-Aug;7(4):238-42. Epub 2013 Jun 13.

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